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product-image-AAA215598_IHC15.jpg IHC (Immunohistochemistry) (IHC analysis of formalin-fixed, paraffin-embedded human placenta. Staining using IDO2/2640 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)

Mouse anti-Human IDO2/Indoleamine 2,3-dioxygenase 2 Monoclonal Antibody | anti-IDO2 antibody

IDO2/Indoleamine 2,3-dioxygenase 2 Mouse Monoclonal Antibody [Clone IDO2/2640]

Gene Names
IDO2; INDOL1
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Synonyms
IDO2/Indoleamine 2,3-dioxygenase 2, Antibody; IDO2/Indoleamine 2,3-dioxygenase 2 Mouse Monoclonal Antibody [Clone IDO2/2640]; 3-dioxygenase 2; 3-dioxygenase-like protein 1; EC 1. 13. 11. ; INDOL 1; Indoleamine 2; Indoleamine 2,3 dioxygenase 2; Indoleamine 2,3 dioxygenase like 1 protein; Indoleamine pyrrole 2,3 dioxygenase like 1; Indoleamine-pyrrole 2; anti-IDO2 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG, kappa
Clone Number
IDO2/2640
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-IDO2 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Recombinant fragment (around aa 200-350) of human IDO2 protein (exact sequence is proprietary)
Cellular Localization
Cytoplasm
Positive Control
Human placenta or liver.
Hu-chromosome Location
8p11.21
Unigene
676257
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(IHC analysis of formalin-fixed, paraffin-embedded human placenta. Staining using IDO2/2640 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)

product-image-AAA215598_IHC15.jpg IHC (Immunohistochemistry) (IHC analysis of formalin-fixed, paraffin-embedded human placenta. Staining using IDO2/2640 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
Related Product Information for anti-IDO2 antibody
IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
19,610 Da
NCBI Official Full Name
Indoleamine 2,3-dioxygenase 2
NCBI Official Synonym Full Names
indoleamine 2,3-dioxygenase 2
NCBI Official Symbol
IDO2
NCBI Official Synonym Symbols
INDOL1
NCBI Protein Information
indoleamine 2,3-dioxygenase 2; IDO-2; indoleamine 2,3-dioxygenase-like 1 protein; indoleamine 2,3-dioxygenase-like protein 1; indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine-pyrrole 2,3-dioxygenase-like protein 1
UniProt Protein Name
Indoleamine 2,3-dioxygenase 2
UniProt Gene Name
IDO2
UniProt Synonym Gene Names
INDOL1; IDO-2
UniProt Entry Name
I23O2_HUMAN

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Product Notes

The IDO2 ido2 (Catalog #AAA215598) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IDO2/Indoleamine 2,3-dioxygenase 2 Mouse Monoclonal Antibody [Clone IDO2/2640] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IDO2/Indoleamine 2,3-dioxygenase 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the IDO2 ido2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IDO2/Indoleamine 2,3-dioxygenase 2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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