IHC (Immunohistochemisry)
(I23O2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of I23O2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human I23O2 Polyclonal Antibody | anti-IDO2 antibody
I23O2 Antibody (C-term)
Gene Names
IDO2; INDOL1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
I23O2, Antibody; I23O2 Antibody (C-term); Indoleamine 2,3-dioxygenase 2; IDO-2; 11311-; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1; IDO2; INDOL1; anti-IDO2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This I23O2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the C-terminal region of human I23O2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
267-295
Sequence Length
172
Applicable Applications for anti-IDO2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(I23O2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of I23O2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(I23O2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of I23O2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(I23O2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the I23O2 antibody detected the I23O2 protein (arrow).)
WB (Western Blot)
(I23O2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the I23O2 antibody detected the I23O2 protein (arrow).)
WB (Western Blot)
(Anti-I23O2 Antibody (C-term)at 1:2000 dilution + human kidney lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 45 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-I23O2 Antibody (C-term)at 1:2000 dilution + human kidney lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 45 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-IDO2 antibody
Along with the enzymes encoded by the INDO (MIM 147435)
and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene
metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007
[PubMed 17499941]).
and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene
metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007
[PubMed 17499941]).
Product Categories/Family for anti-IDO2 antibody
References
Cetindere, T., et al. Cell. Signal. 22(2):197-211(2010)
Huttunen, R., et al. Shock 33(2):149-154(2010)
Witkiewicz, A.K., et al. J. Am. Coll. Surg. 208(5):781-787(2009)
Metz, R., et al. Cancer Res. 67(15):7082-7087(2007)
Ball, H.J., et al. Gene 396(1):203-213(2007)
Huttunen, R., et al. Shock 33(2):149-154(2010)
Witkiewicz, A.K., et al. J. Am. Coll. Surg. 208(5):781-787(2009)
Metz, R., et al. Cancer Res. 67(15):7082-7087(2007)
Ball, H.J., et al. Gene 396(1):203-213(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45424
NCBI Official Full Name
indoleamine 2,3-dioxygenase 2
NCBI Official Synonym Full Names
indoleamine 2,3-dioxygenase 2
NCBI Official Symbol
IDO2
NCBI Official Synonym Symbols
INDOL1
NCBI Protein Information
indoleamine 2,3-dioxygenase 2
UniProt Protein Name
Indoleamine 2,3-dioxygenase 2
UniProt Gene Name
IDO2
UniProt Synonym Gene Names
INDOL1; IDO-2
UniProt Entry Name
I23O2_HUMAN
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Product Notes
The IDO2 ido2 (Catalog #AAA287912) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 267-295. The I23O2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's I23O2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the IDO2 ido2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "I23O2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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