IHC (Immunohiostchemistry)
(Anti-IGF1 Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Mouse anti-Human, Mouse IGF1R / IGF1 Receptor Monoclonal Antibody | anti-IGF1R antibody
Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor
Gene Names
IGF1R; IGFR; CD221; IGFIR; JTK13
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Western Blot, Immunohistochemistry
Purity
Protein A Purified
Synonyms
IGF1R / IGF1 Receptor, Antibody; Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor; Anti-IGF1R / IGF1 Receptor Antibody (aa1264-1367, clone JBW902) IHC-plus; IGF1R; CD221 antigen; CD221; IGF1 Receptor; IGFR; IGF-I receptor; Soluble IGF1R variant 1; Soluble IGF1R variant 2; Type 1 IGF receptor; IGFIR; JTK13; Human IGF1R; anti-IGF1R antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
JBW902
Specificity
Recognizes human IGF-1 receptor beta chain, MW 95kD. Recognizes transmembrane domain. Not expected to cross-react with INSR based on sequence homology.
Purity/Purification
Protein A Purified
Form/Format
Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, before the addition of glycerol to 8.4%
Concentration
1 mg/ml (varies by lot)
Sequence Length
1367
Applicable Applications for anti-IGF1R antibody
IP (Immunoprecipitation), WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
GST fusion protein corresponding to residues 1264-1367 of human IGF-1 Receptor.
Immunogen Type
Fusion protein
Immunogen
IGF1R / IGF1 Receptor antibody was raised against gST fusion protein corresponding to residues 1264-1367 of human IGF-1 Receptor.
Antigen Modification
aa1264-1367
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Anti-IGF1 Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohiostchemistry)
(Anti-IGF1 Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-IGF1 Receptor antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-IGF1 Receptor antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-IGF1R antibody
IGF1R, an insulin receptor type protein kinase, mediates IGF1 stimulated cell proliferation and differentiation. IGF1R binds insulin-like growth factor I with high affinity and IGF II with a lower affinity. The protein has been shown to be highly expressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Product Categories/Family for anti-IGF1R antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
154,793 Da
NCBI Official Full Name
insulin-like growth factor 1 receptor isoform 1
NCBI Official Synonym Full Names
insulin-like growth factor 1 receptor
NCBI Official Symbol
IGF1R
NCBI Official Synonym Symbols
IGFR; CD221; IGFIR; JTK13
NCBI Protein Information
insulin-like growth factor 1 receptor; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
UniProt Protein Name
Insulin-like growth factor 1 receptor
UniProt Gene Name
IGF1R
UniProt Synonym Gene Names
IGF-I receptor
UniProt Entry Name
IGF1R_HUMAN
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Product Notes
The IGF1R igf1r (Catalog #AAA51834) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IGF1R / IGF1 Receptor can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IGF1R igf1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGF1R / IGF1 Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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