IHC (Immunohiostchemistry)
(Immunohistochemistry of Ikaros in paraffin-embedded Human tonsil using Ikaros Rabbit mAb at dilution 1/50)
Ikaros Monoclonal Antibody | anti-Ikaros antibody
Ikaros Rabbit mAb
Gene Names
IKZF1; IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
Ikaros, Antibody; Ikaros Rabbit mAb; IK1; LYF1; LyF-1; CVID13; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452; anti-Ikaros antibody
Host
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
S08-5E4
Purity/Purification
Affinity Purified
Form/Format
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-Ikaros antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide of human Ikaros
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Ikaros in paraffin-embedded Human tonsil using Ikaros Rabbit mAb at dilution 1/50)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Ikaros in paraffin-embedded Human tonsil using Ikaros Rabbit mAb at dilution 1/50)
WB (Western Blot)
(Western blot detection of Ikaros in CHO-K1,Jurkat cell lysates using Ikaros Rabbit mAb(1:500 diluted).Predicted band size:58kDa.Observed band size:50-70kDa.)
WB (Western Blot)
(Western blot detection of Ikaros in CHO-K1,Jurkat cell lysates using Ikaros Rabbit mAb(1:500 diluted).Predicted band size:58kDa.Observed band size:50-70kDa.)
Related Product Information for anti-Ikaros antibody
Transcription regulator of hematopoietic cell differentiation (PubMed:17934067). Binds gamma-satellite DNA (PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms (PubMed:17135265, PubMed:17934067).
Product Categories/Family for anti-Ikaros antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
519
NCBI Official Full Name
DNA-binding protein Ikaros
NCBI Official Synonym Full Names
IKAROS family zinc finger 1 (Ikaros)
NCBI Official Symbol
IKZF1
NCBI Official Synonym Symbols
IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
NCBI Protein Information
DNA-binding protein Ikaros; CLL-associated antigen KW-6; ikaros family zinc finger protein 1; lymphoid transcription factor LyF-1; protein phosphatase 1, regulatory subunit 92; zinc finger protein, subfamily 1A, 1 (Ikaros)
UniProt Protein Name
DNA-binding protein Ikaros
UniProt Gene Name
IKZF1
UniProt Synonym Gene Names
IK1; IKAROS; LYF1; ZNFN1A1
UniProt Entry Name
IKZF1_HUMAN
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Product Notes
The Ikaros ikzf1 (Catalog #AAA314389) is an Antibody produced from Recombinant Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ikaros Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Ikaros can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Ikaros ikzf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ikaros, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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