Mouse anti-Human Ikaros Monoclonal Antibody | anti-Ikaros antibody

Ikaros (C-term) Mouse mAb

Cat. Num. AAA320328

• Gene Names: IKZF1; IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
• Reactivity: Human
• Applications: Immunoprecipitation, Western Blot
• Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
• Synonyms: Ikaros, Antibody; Ikaros (C-term) Mouse mAb; CLL associated antigen KW 6; DNA-binding protein Ikaros; hIk 1; hIk-1; Hs.54452; IK1; Ikaros (zinc finger protein); IKAROS; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; Ikzf1; IKZF1_HUMAN; LYF1; Lymphoid transcription factor LyF-1; PRO0758; Zinc finger protein subfamily 1A 1 (Ikaros); zinc finger protein subfamily 1A 1; Zinc finger protein, subfamily 1A, member 1; ZNFN1A1.; anti-Ikaros antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: This antibody detects endogenous levels of Ikaros(C-terminus) and does not cross-react with related proteins.
• Purity/Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-Ikaros antibody: IP (Immunoprecipitation), WB (Western Blot)
• Immunogen: Purified recombinant human Ikaros(C-terminus) protein fragments expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

IP (Immunoprecipitation)

(Immunoprecipitation analysis of Hela cell lysate using Ikaros (C-terminus) mouse mAb.)

WB (Western Blot)

(Western blot detection of Ikaros(C-terminus) in Ramos and Jurkat cell lysates using Ikaros(C-terminus) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 58KDa.)

Related Product Information for anti-Ikaros antibody

This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding

Product Categories/Family for anti-Ikaros antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 3913926
• NCBI GeneID: 10320
• UniProt Accession #: Q13422; O00598; Q53XL2; Q69BM4; Q8WVA3; A4D260; B4E0Z1; D3DVM5
• Molecular Weight: 519
• NCBI Official Full Name: DNA-binding protein Ikaros
• NCBI Official Synonym Full Names: IKAROS family zinc finger 1 (Ikaros)
• NCBI Official Symbol: IKZF1
• NCBI Official Synonym Symbols: IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452
• NCBI Protein Information: DNA-binding protein Ikaros; CLL-associated antigen KW-6; ikaros family zinc finger protein 1; lymphoid transcription factor LyF-1; protein phosphatase 1, regulatory subunit 92; zinc finger protein, subfamily 1A, 1 (Ikaros)
• UniProt Protein Name: DNA-binding protein Ikaros
• UniProt Gene Name: IKZF1
• UniProt Synonym Gene Names: IK1; IKAROS; LYF1; ZNFN1A1
• UniProt Entry Name: IKZF1_HUMAN