WB (Western Blot)
(U-937 cells were subjected to SDS PAGE followed by western blot with AAA247953 (IL-17 antibody) at dilution of 1:500)
Mouse IL-17 Monoclonal Antibody | anti-IL-17 antibody
IL-17 Mouse Monoclonal
Reactivity
Human; other species are not tested.
Applications
Flow Cytometry, Functional Assay, Western Blot, ELISA
Purity
>=95% as determined by SDS-PAGE, Protein A+G purification
Synonyms
IL-17, Antibody; IL-17 Mouse Monoclonal; CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A; anti-IL-17 antibody
Host
Mouse
Reactivity
Human; other species are not tested.
Clonality
Monoclonal
Isotype
IgG1
Specificity
Please decide the specificity by homology.
Purity/Purification
>=95% as determined by SDS-PAGE, Protein A+G purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Applicable Applications for anti-IL-17 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot), ELISA
Immunogen
interleukin 17A
Preparation and Storage
-20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
WB (Western Blot)
(U-937 cells were subjected to SDS PAGE followed by western blot with AAA247953 (IL-17 antibody) at dilution of 1:500)
WB (Western Blot)
(U-937 cells were subjected to SDS PAGE followed by western blot with AAA247953 (IL-17 antibody) at dilution of 1:500)
Related Product Information for anti-IL-17 antibody
IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
18 kDa
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Product Notes
The IL-17 (Catalog #AAA247953) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL-17 Mouse Monoclonal reacts with Human; other species are not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's IL-17 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IL-17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-17, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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