Rabbit anti-Human IL11RA, IgG1 Monoclonal Antibody | anti-IL11RA antibody

Anti-IL11RA antibody (DMC282), IgG1 Chimeric mAb

Cat. Num. AAA47509

• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay
• Purity: Purified from cell culture supernatant by affinity chromatography.; Purity: Test: SDS-PAGE & Coomassie blue staining ;; Specification: Target protein band (s) >95.0 % ;; Result: Pass
• Synonyms: IL11RA, IgG1, Antibody; Anti-IL11RA antibody (DMC282), IgG1 Chimeric mAb; IL-11 R alpha; IL-11 RA; IL11RA; Interleukin-11 receptor subunit alpha; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; anti-IL11RA antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit/Human Fc chimeric IgG1
• Purity/Purification: Purified from cell culture supernatant by affinity chromatography.; Purity: Test: SDS-PAGE & Coomassie blue staining ;; Specification: Target protein band (s) >95.0 % ;; Result: Pass
• Form/Format: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization.
• Concentration: 0.472mg/mL (varies by lot)

• Applicable Applications for anti-IL11RA antibody: FCM/FACS (Flow Cytometry)
• Visual Inspection: Test: Lyophilization; Specification: Dried white powder; Result: Pass; ; Test: Vial Label; Specification: Label aligned and complete; Result: Pass; ; Test: Bottle sealing (manual check); Specification: Sealed tight; Result: Pass
• Quantity: Test: A280; Specification: <specified quantity; Result: Pass
• Other properties: Test: pH; Specification: 7.4 ± 0.5; Result: Pass
• Reconstitution: 1.Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5 min at room temperature to ensure the Lyophilized sample to settle down at the bottom of the tube; 2.Dissolved Lyophilized protein sample in sterile water based on the recommended volume 21.19 µL; 3.After adding sterile water, cover the lid and mix them by gently tapping the tube for 5-10 times. Note: Do not vortex or vigorously pipette sample
• Preparation and Storage: Store at -20°C to -80°C for 12 months in lyphilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

FCM/FACS (Flow Cytometry)

(Figure 1. IL11RA protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with Anti-IL11RA (DMC282) on Expi293 cells transfected with human IL11RA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).)

Related Product Information for anti-IL11RA antibody

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.

Product Categories/Family for anti-IL11RA antibody

Lead Antibody Molecules