IHC (Immunohiostchemistry)
(IL-1b Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue)
Mouse anti-Human IL1b Monoclonal Antibody | anti-IL1b antibody
IL1b (BSB-139)
Reactivity
Human
Synonyms
IL1b, Antibody; IL1b (BSB-139); il-1b; il1b; anti-il1b; anti-il-1b; il1b antibody; anti-il-1b antibody; cytokine storm; cytokine storm syndrome; cytokine storm antibody; cytokine storm antibodies; sars-cov-2 receptors; sars cov-2 receptors; covid-19 receptors; sars-cov-2 antibodies sars-cov-2 ihc; sars-cov-2 immunohistochemistry; IL1B; sc52012; IL-1beta; IL-1 beta; IL-1b; IL-1 b; IL 1beta; IL1beta; Catabolin; IL 1; IL 1 beta; IL1 BETA; IL1F2; interleukin 1 beta; preinterleukin 1 beta; pro interleukin 1 beta; il;; anti-IL1b antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
BSB-139
Form/Format
Paraffin, Frozen
IL-1b antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
IL-1b antibody is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Recombinant protein corresponding to the IL-1? of human origin.
Control
Colon, Pancreas, Liver, Stomach, Brain, Testis, Lung, Transitional Cell Carcinoma, Tonsil
Localization
Cytoplasmic
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
IHC (Immunohiostchemistry)
(IL-1b Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue)
IHC (Immunohiostchemistry)
(IL-1b Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue)
Dilution Info
Dilution Info
Related Product Information for anti-IL1b antibody
IL-1b has multiple functions as a major pro-inflammatory cytokine regulated by NFKB. The 31 kDa precursor is biologically inactive in the cytosol, and is processed to its active 17 kDa mature form by Caspase 1 in special lysosomes. The beta-barrel cytokine is secreted to participate in pathways of angiogenesis, antigen presentation, adhesion molecule expression, inflammatory cell activity, and expression of matrix degrading enzymes.
IL-1b antibody expression is found in tumor-infiltrating myeloid cells, which then produce VEGF and other angiogenesis-related factors, promoting growth in multiple tumor types. IL-1b has a role in tumor metastasis and helps maintain an inflammatory tumor environment, but has also demonstrated an anti-tumorigenic function in recruiting immune cells and driving activation of the Th1 response against B cell myeloma and lymphoma. Pathogen-Associated Molecular Patterns can also initiate expression of IL-1b antibody, helping to accumulate neutrophils and promote inflammation and fibrosis at the infection site.
IL-1b antibody expression is found in tumor-infiltrating myeloid cells, which then produce VEGF and other angiogenesis-related factors, promoting growth in multiple tumor types. IL-1b has a role in tumor metastasis and helps maintain an inflammatory tumor environment, but has also demonstrated an anti-tumorigenic function in recruiting immune cells and driving activation of the Th1 response against B cell myeloma and lymphoma. Pathogen-Associated Molecular Patterns can also initiate expression of IL-1b antibody, helping to accumulate neutrophils and promote inflammation and fibrosis at the infection site.
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Product Notes
The IL1b (Catalog #AAA59350) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL1b (BSB-139) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "IL1b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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