Application Data
(Fig 2: Cell surface staining of HepG2 cells. 2ug of antibody was used. Green Isotype control. Red Insulin Receptor antibody.)
Mouse anti-Human Insulin Receptor Monoclonal Antibody | anti-INSR antibody
Mouse Monoclonal Antibody to Insulin Receptor (Clone: IR-1)
Gene Names
INSR; HHF5; CD220
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein G Chromatography
Synonyms
Insulin Receptor, Antibody; Mouse Monoclonal Antibody to Insulin Receptor (Clone: IR-1); Anti-Insulin Receptor Mouse Monoclonal Antibody; 10-7605; Insulin; CD220; HHF5; HIR A; INSR; Insulin receptor; IR; anti-INSR antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
IR-1
Purity/Purification
Protein G Chromatography
Form/Format
0.5ug/ml of MAb purified by Protein G. Prepared in PBS with 0.05% BSA & 0.05% azide
Sequence Length
1382
Applicable Applications for anti-INSR antibody
FCM/FACS (Flow Cytometry)
Antigen
Insulin receptor
Preparation and Storage
Store at 2 to 8 degree C.
For long-term storage, store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous.
For long-term storage, store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous.
Application Data
(Fig 2: Cell surface staining of HepG2 cells. 2ug of antibody was used. Green Isotype control. Red Insulin Receptor antibody.)
Application Data
(Fig 2: Cell surface staining of HepG2 cells. 2ug of antibody was used. Green Isotype control. Red Insulin Receptor antibody.)
Application Data
(Fig 1: Cell surface staining of PBMC, lymphocytes gated. 1ug of antibody was used. Green Isotype control. Red Insulin Receptor antibody.)
Application Data
(Fig 1: Cell surface staining of PBMC, lymphocytes gated. 1ug of antibody was used. Green Isotype control. Red Insulin Receptor antibody.)
Related Product Information for anti-INSR antibody
The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular subunit and an extracellular subunit, which is disulfide-linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intra-cellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin. Type 1 diabetes is an auto-immune condition of the endocrine pancreas that results in destruction of insulin secreting cells and a progressive loss in insulin-sensitive glucose uptake by cells.
Product Categories/Family for anti-INSR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
insulin receptor isoform Long preproprotein
NCBI Official Synonym Full Names
insulin receptor
NCBI Official Symbol
INSR
NCBI Official Synonym Symbols
HHF5; CD220
NCBI Protein Information
insulin receptor
UniProt Protein Name
Insulin receptor
UniProt Gene Name
INSR
UniProt Synonym Gene Names
IR
UniProt Entry Name
INSR_HUMAN
Similar Products
Product Notes
The INSR insr (Catalog #AAA78499) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal Antibody to Insulin Receptor (Clone: IR-1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Insulin Receptor can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the INSR insr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insulin Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.