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product-image-AAA120067_SDS_PAGE13.jpg SDS-PAGE (SDS PAGE for Isatuximab)

Chimeric anti-Human Isatuximab Monoclonal Antibody | anti-CD38 antibody

Research Grade Isatuximab

Gene Names
CD38; T10; ADPRC 1
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Isatuximab, Antibody; Research Grade Isatuximab; SAR-650984; hu38SB19; Cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; T10; 2'-phospho-cyclic-ADP-ribose transferase; CD38; ADPRC 1; ADP-ribosyl cyclase 1; 2'-phospho-ADP-ribosyl cyclase; anti-CD38 antibody
Ordering
Host
Chimeric
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
CAS
1461640-62-9
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

SDS-PAGE

(SDS PAGE for Isatuximab)

product-image-AAA120067_SDS_PAGE13.jpg SDS-PAGE (SDS PAGE for Isatuximab)

Bioactivity

(Detects Human CD38 in direct ELISAs.)

product-image-AAA120067_BIOACTIVITY15.jpg Bioactivity (Detects Human CD38 in direct ELISAs.)
Product Categories/Family for anti-CD38 antibody
References
Isatuximab for the treatment of relapsed/refractory multiple myeloma, PMID: 33111607
Isatuximab: First Approval, PMID: 32347476
Isatuximab plus carfilzomib/dexamethasone versus carfilzomib/dexamethasone in patients with relapsed/refractory multiple myeloma: IKEMA Phase III study design, PMID: 31833394
Therapeutic Opportunities with Pharmacological Inhibition of CD38 with Isatuximab, PMID: 31779273
The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma, PMID: 30692097

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
952
UniProt Accession #
Molecular Weight
300
NCBI Official Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
NCBI Official Synonym Full Names
CD38 molecule
NCBI Official Symbol
CD38
NCBI Official Synonym Symbols
T10; ADPRC 1
NCBI Protein Information
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen (p45); NAD(+) nucleosidase; ADP-ribosyl cyclase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cycli
UniProt Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
UniProt Gene Name
CD38
UniProt Synonym Gene Names
ADPRC 1; cADPr hydrolase 1
UniProt Entry Name
CD38_HUMAN

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Product Notes

The CD38 cd38 (Catalog #AAA120067) is an Antibody produced from Chimeric and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Isatuximab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Isatuximab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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