IF (Immunofluorescence)
(Immunofluorescence analysis of U-2 OS cells using Lamin A/C Monoclonal Antibody at dilution of 1:500.)
Mouse anti-Human Lamin A/C Monoclonal Antibody | anti-LMNA antibody
Lamin A/C Monoclonal Antibody
Gene Names
LMNA; FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Protein A/G Purification
Synonyms
Lamin A/C, Antibody; Lamin A/C Monoclonal Antibody; Prelamin-A/C; LMNA; LMN1; Lamin A/C; anti-LMNA antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F1
Purity/Purification
Protein A/G Purification
Form/Format
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH 7.4
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-LMNA antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant human Lamin A/C protein expressed by E coli
Preparation and Storage
Store at -20 degree C Valid for 12 months. Avoid freeze/thaw cycles. Protected from prolonged exposure to light.
IF (Immunofluorescence)
(Immunofluorescence analysis of U-2 OS cells using Lamin A/C Monoclonal Antibody at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U-2 OS cells using Lamin A/C Monoclonal Antibody at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using Lamin A/C Monoclonal Antibody at dilution of 1:500.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HeLa cells using Lamin A/C Monoclonal Antibody at dilution of 1:500.)
WB (Western Blot)
(Western blot with Anti Lamin A/C Monoclonal Antibody at dilution of 1:3000. Lane 1: SH-SY5Y cell lysate, Lane 2: HL-60 cell lysate, Lane 3: U-87 MG cell lysate, Lane 4: Hep G2 cell lysate.)
WB (Western Blot)
(Western blot with Anti Lamin A/C Monoclonal Antibody at dilution of 1:3000. Lane 1: SH-SY5Y cell lysate, Lane 2: HL-60 cell lysate, Lane 3: U-87 MG cell lysate, Lane 4: Hep G2 cell lysate.)
Related Product Information for anti-LMNA antibody
Lamin A/C is also named as LMNA, or LMN1. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. The lack of lamin A/C can be as a novel marker for undifferentiated embryonic stem cells and lamin A/C expression is as an early indicator of differentiation (PMID: 16179429). Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 74 kDa, 65 kDa, 70 kDa and 64 kDa. This antibody can recognize 4 isoforms of Lamin A/C.
Product Categories/Family for anti-LMNA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,65kDa
NCBI Official Full Name
lamin isoform D
NCBI Official Synonym Full Names
lamin A/C
NCBI Official Symbol
LMNA
NCBI Official Synonym Symbols
FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B
NCBI Protein Information
lamin; 70 kDa lamin; prelamin-A/C; lamin A/C-like 1; renal carcinoma antigen NY-REN-32
UniProt Protein Name
Prelamin-A/C
UniProt Gene Name
LMNA
UniProt Synonym Gene Names
LMN1
UniProt Entry Name
LMNA_HUMAN
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Product Notes
The LMNA lmna (Catalog #AAA179738) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Lamin A/C Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lamin A/C can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the LMNA lmna for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lamin A/C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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