IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 antibody with DAB staining.)
Mouse MCL1 Monoclonal Antibody | anti-MCL1 antibody
MCL1 antibody
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Synonyms
MCL1, Antibody; MCL1 antibody; Monoclonal MCL1; Anti-MCL1; MCL-1; MCL 1; Myeloid cell leukemia 1; MCL1; anti-MCL1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8C6; 8C6D4B1
Form/Format
Purified antibody supplied in PBS containing 0.03% sodium azide.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
271
Applicable Applications for anti-MCL1 antibody
WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
Biological Significance
MCL1 is a protein which belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.
Cross-Reactivity
Human
Immunogen
MCL1 antibody was raised in Mouse using a purified recombinant fragment of human MCL-1 expressed in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 antibody with DAB staining.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human lymphnode tissues using MCL1 antibody with DAB staining.)
WB (Western Blot)
(Western Blot showing MCL1 antibody used against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.)
WB (Western Blot)
(Western Blot showing MCL1 antibody used against Hela (1), BCBL-1 (2), Jurkat (3) and HL60 (4) cell lysate.)
Related Product Information for anti-MCL1 antibody
Mouse monoclonal MCL1 antibody
Product Categories/Family for anti-MCL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
28,662 Da
UniProt Protein Name
Induced myeloid leukemia cell differentiation protein Mcl-1
UniProt Gene Name
MCL1
UniProt Synonym Gene Names
BCL2L3; Bcl2-L-3
UniProt Entry Name
MCL1_HUMAN
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Product Notes
The MCL1 mcl1 (Catalog #AAA74819) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MCL1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA. Researchers should empirically determine the suitability of the MCL1 mcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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