IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with MCM2 Mouse Monoclonal Antibody (MCM2/3678). Inset: PBS instead of primary antibody, secondary only control.)
Mouse anti-Human MCM7 Monoclonal Antibody | anti-MCM2 antibody
MCM7 (ProliferationMarker) Mouse Monoclonal Antibody [Clone MCM2/3678]
Gene Names
MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
MCM7, Antibody; MCM7 (ProliferationMarker) Mouse Monoclonal Antibody [Clone MCM2/3678]; MCM7 (ProliferationMarker); BM28; CCNL1; CDC like 1; cdc19; CDCL1; Cell devision cycle like 1; Cyclin like 1; DNA replication licensing factor MCM2; KIAA0030; Minichromosome maintenance complex component 2; Minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance protein 2 homolog; Mitotin; Nuclear protein BM28; anti-MCM2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
MCM2/3678
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-MCM2 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment (aa 650-750) of human MCM2 protein (exact sequence is proprietary)
Cellular Localization
Nuclear
Positive Control
MCF-7, Jurkat or Ramos cells. Human tonsil.
Hu-chromosome Location
3q21.3
Unigene
477481
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with MCM2 Mouse Monoclonal Antibody (MCM2/3678). Inset: PBS instead of primary antibody, secondary only control.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human tonsil stained with MCM2 Mouse Monoclonal Antibody (MCM2/3678). Inset: PBS instead of primary antibody, secondary only control.)
Related Product Information for anti-MCM2 antibody
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101,896 Da
NCBI Official Full Name
DNA replication licensing factor MCM2
NCBI Official Synonym Full Names
minichromosome maintenance complex component 2
NCBI Official Symbol
MCM2
NCBI Official Synonym Symbols
BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
NCBI Protein Information
DNA replication licensing factor MCM2; cyclin-like 1; nuclear protein BM28; cell devision cycle-like 1; minichromosome maintenance protein 2 homolog; minichromosome maintenance deficient 2 (mitotin); MCM2 minichromosome maintenance deficient 2, mitotin
UniProt Protein Name
DNA replication licensing factor MCM2
UniProt Gene Name
MCM2
UniProt Synonym Gene Names
BM28; CCNL1; CDCL1; KIAA0030
UniProt Entry Name
MCM2_HUMAN
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Product Notes
The MCM2 mcm2 (Catalog #AAA215795) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MCM7 (ProliferationMarker) Mouse Monoclonal Antibody [Clone MCM2/3678] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCM7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MCM2 mcm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCM7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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