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ICC (Immunocytochemistry)
(Anti-MCM7 antibody, AAA45088, ICCICC: HELA Cell)
Rabbit anti-Human MCM7 Polyclonal Antibody | anti-MCM7 antibody
Anti-MCM7 antibody
Gene Names
MCM7; MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
MCM7, Antibody; Anti-MCM7 antibody; DNA replication licensing factor MCM7; minichromosome maintenance complex component 7; CDABP0042 antibody; CDC 47 antibody; CDC47 antibody; CDC47 homolog antibody; Cdc47, S. cerevisiae, homolog of antibody; DNA replication licensing factor MCM7 antibody; Homolog of S. cerevisiae Cdc47 antibody; MCM 2 antibody; MCM 7 antibody; MCM2 antibody; MCM2, formerly antibody; Mcm7 antibody; MCM7 minichromosome maintenance deficient 7 antibody; MCM7_HUMAN antibody; Minichromosome Maintainence 7 antibody; Minichromosome maintainence, S. cerevisiae, homolog of antibody; Minichromosome maintenance complex component 7 antibody; Minichromosome maintenance deficient 7 antibody; Minichromosome maintenance protein 7 antibody; P1.1 MCM3 antibody; P1.1-MCM3 antibody; P1CDC47 antibody; P85MCM antibody; PNAS 146 antibody; PNAS146 antibody; anti-MCM7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
719
Applicable Applications for anti-MCM7 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MCM7 (699-719aa DEYEELNVWQVNASRTRITFV).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ICC (Immunocytochemistry)
(Anti-MCM7 antibody, AAA45088, ICCICC: HELA Cell)
ICC (Immunocytochemistry)
(Anti-MCM7 antibody, AAA45088, ICCICC: HELA Cell)
ICC (Immunocytochemistry)
(Anti-MCM7 antibody, AAA45088, ICCICC: MCF-7 Cell)
ICC (Immunocytochemistry)
(Anti-MCM7 antibody, AAA45088, ICCICC: MCF-7 Cell)
WB (Western Blot)
(Anti-MCM7 antibody, AAA45088, Western blottingLane 1: COLO320 Cell LysateLane 2: SW620 Cell LysateLane 3: HELA Cell LysateLane 4: 22RVL Cell LysateLane 5: 293T Cell LysateLane 6: U937 Cell LysateLane 7: JURKAT Cell LysateLane 8: RAJI Cell Lysate)
WB (Western Blot)
(Anti-MCM7 antibody, AAA45088, Western blottingLane 1: COLO320 Cell LysateLane 2: SW620 Cell LysateLane 3: HELA Cell LysateLane 4: 22RVL Cell LysateLane 5: 293T Cell LysateLane 6: U937 Cell LysateLane 7: JURKAT Cell LysateLane 8: RAJI Cell Lysate)
IHC (Immunohistochemistry)
(Anti-MCM7 antibody, AAA45088, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-MCM7 antibody, AAA45088, IHC(P)IHC(P): Human Lung Cancer Tissue)
Related Product Information for anti-MCM7 antibody
Description: Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM7(MCM7) detection. Tested with WB, IHC-P, ICC in Human.
Background: MCM7(Minichromosome Maintenance, s. Cerevisiae, homolog of, 7), also called CDC47, FORMERLY, is one of the highly conserved mini-chromosome maintenance proteins(MCM) that are essential for the initiation of eukaryotic genome replication. The MCM7 gene is mapped on 7q22.1. MCM7 plays a pivotal role in the G1/S phase transition, orchestrating the correct assembly of replication forks on chromosomal DNA and ensuring that all the genome is replicated once and not more than once at each cell cycle. The MCM7 gene contains 15 exons. The miRNAs MIR106B, MIR93, and MIR25 are clustered in a 5-prime to 3-prime orientation within intron 13. Petrocca et al.(2008) found that MCM7 and the precursors of microRNAs(miRNAs) MIR106B, MIR93, and MIR25, all of which arise from intron 13 of the MCM7 gene, were overexpressed with almost perfect correlation in 5 of 10 human gastric tumors.
Background: MCM7(Minichromosome Maintenance, s. Cerevisiae, homolog of, 7), also called CDC47, FORMERLY, is one of the highly conserved mini-chromosome maintenance proteins(MCM) that are essential for the initiation of eukaryotic genome replication. The MCM7 gene is mapped on 7q22.1. MCM7 plays a pivotal role in the G1/S phase transition, orchestrating the correct assembly of replication forks on chromosomal DNA and ensuring that all the genome is replicated once and not more than once at each cell cycle. The MCM7 gene contains 15 exons. The miRNAs MIR106B, MIR93, and MIR25 are clustered in a 5-prime to 3-prime orientation within intron 13. Petrocca et al.(2008) found that MCM7 and the precursors of microRNAs(miRNAs) MIR106B, MIR93, and MIR25, all of which arise from intron 13 of the MCM7 gene, were overexpressed with almost perfect correlation in 5 of 10 human gastric tumors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,643 Da
NCBI Official Full Name
DNA replication licensing factor MCM7
NCBI Official Synonym Full Names
minichromosome maintenance complex component 7
NCBI Official Symbol
MCM7
NCBI Official Synonym Symbols
MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
NCBI Protein Information
DNA replication licensing factor MCM7; CDC47 homolog; homolog of S. cerevisiae Cdc47; minichromosome maintenance deficient 7; protein phosphatase 1, regulatory subunit 104
UniProt Protein Name
DNA replication licensing factor MCM7
UniProt Gene Name
MCM7
UniProt Synonym Gene Names
CDC47; MCM2
UniProt Entry Name
MCM7_HUMAN
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Product Notes
The MCM7 mcm7 (Catalog #AAA45088) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MCM7 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MCM7 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MCM7 mcm7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCM7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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