Rabbit anti-Mouse MD1 Monoclonal Antibody | anti-LY86 antibody
Recombinant Anti-MD1 Antibody, Rabbit Monoclonal
Gene Names
Ly86; MD1; MD-1
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
MD1, Antibody; Recombinant Anti-MD1 Antibody, Rabbit Monoclonal; LY86/MD-1 Antibody, Rabbit MAb; lymphocyte antigen 86; Anti-MD-1 Antibody; Anti-MD1 Antibody; anti-LY86 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
241
Specificity
Mouse LY86/MD1
Purity/Purification
Protein A
Form/Format
0.2um filtered solution in PBS
Applicable Applications for anti-LY86 antibody
ELISA
Immunogen
Recombinant Mouse LY86 protein ( )
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LY86 (rM LY86).
Preparation and Storage
This antibody can be stored at 2 degrees C to 8 degrees for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degrees to -80 degrees C. Preservative-Free. Avoid repeated freeze-thaw cycles
Related Product Information for anti-LY86 antibody
MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is anchored by radioprotective 15 (RP15) which is a molecule containing leucine-rich repeats and is expressed on B cells, dendritic cells, and macrophages, while MD-2 is associated with TLR4. MD-1 is required for efficient RP15 cell surface expression and function. It is indicated that the RP15/MD1 complex, in conjunction with TLR4, mediates the innate immune response to LPS in B cells, and also plays a role in protecting against apoptosis, B-cell proliferation, etc. Mouse MD-1 cDNA encodes a 162 amino acid precursor protein with a putative 19 aa signal peptide and two potential N-linked glycosylation sites. It shares 4% and 66% amino acid sequence identity with chicken and human MD-1 respectively. MD-1 is mainly expressed in the spleen, and also detectable in the liver, brain, thymus, and kidney.
References
Miura Y., et al., (1998), RP105 is associated with MD-1 and transmits an activation signal in human B cells. Blood 92:2815-2822.Begum N.A., et al., (1999), Human MD-1 homologue is a BCG-regulated gene product in monocytes: Its identification by differential display.Biochem. Biophys. Res. Commun. 256:325-329.Mungall A.J., et al., (2003), The DNA sequence and analysis of human chromosome 6.Nature 425:805-811.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,811 Da
NCBI Official Full Name
lymphocyte antigen 86
NCBI Official Synonym Full Names
lymphocyte antigen 86
NCBI Official Symbol
Ly86
NCBI Official Synonym Symbols
MD1; MD-1
NCBI Protein Information
lymphocyte antigen 86; ly-86; protein MD-1
UniProt Protein Name
Lymphocyte antigen 86
UniProt Gene Name
Ly86
UniProt Synonym Gene Names
Md1; Ly-86
UniProt Entry Name
LY86_MOUSE
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Product Notes
The LY86 ly86 (Catalog #AAA257074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-MD1 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MD1 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the LY86 ly86 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MD1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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