Application Data
(Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.)
Mouse MKP-3 Monoclonal Antibody | anti-MKP-3 antibody
MKP-3 Antibody
Gene Names
DUSP6; MKP3; PYST1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Purity
ProA affinity purified
Synonyms
MKP-3, Antibody; MKP-3 Antibody; Dual specificity phosphatase 6 antibody; Dual specificity phosphatase 6 isoform a antibody; Dual specificity protein phosphatase 6 antibody; Dual specificity protein phosphatase PYST1 antibody; DUS6_HUMAN antibody; DUSP 6 antibody; DUSP 6a antibody; Dusp6 antibody; DUSP6a antibody; HH19 antibody; MAP kinase phosphatase 3 antibody; Mitogen activated protein kinase phosphatase 3 antibody; Mitogen-activated protein kinase phosphatase 3 antibody; MKP 3 antibody; MKP-3 antibody; MKP3 antibody; PYST 1 antibody; PYST1 antibody; Serine/threonine specific protein phosphatase antibody; hide; anti-MKP-3 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
3G1
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-MKP-3 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Peptide
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Application Data
(Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.)
Application Data
(Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.)
WB (Western Blot)
(Western blot analysis of MKP-3 expression in non-transfected (A) and human MKP-3 transfected (B) 293T whole cell lysates.)
WB (Western Blot)
(Western blot analysis of MKP-3 expression in non-transfected (A) and human MKP-3 transfected (B) 293T whole cell lysates.)
Related Product Information for anti-MKP-3 antibody
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q21.33 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.
Product Categories/Family for anti-MKP-3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,320 Da
NCBI Official Full Name
dual specificity protein phosphatase 6 isoform a
NCBI Official Synonym Full Names
dual specificity phosphatase 6
NCBI Official Symbol
DUSP6
NCBI Official Synonym Symbols
MKP3; PYST1
NCBI Protein Information
dual specificity protein phosphatase 6; MAP kinase phosphatase 3; dual specificity protein phosphatase PYST1; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 3
UniProt Protein Name
Dual specificity protein phosphatase 6
UniProt Gene Name
DUSP6
UniProt Synonym Gene Names
MKP3; PYST1; MAP kinase phosphatase 3; MKP-3
UniProt Entry Name
DUS6_HUMAN
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Product Notes
The MKP-3 dusp6 (Catalog #AAA311993) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MKP-3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MKP-3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the MKP-3 dusp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKP-3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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