IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human lung cancer (left) and esophagus cancer (right). showing nuclear localization with DAB staining using MLL Monoclonal Antibody.)
Mouse anti-Human MLL Monoclonal Antibody | anti-MLL antibody
MLL Monoclonal Antibody
Gene Names
KMT2A; HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; MLL/GAS7; TET1-MLL
Reactivity
Human
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
MLL, Antibody; MLL Monoclonal Antibody; Histone-lysine N-methyltransferase MLL; MLL; ALL1; CXXC7; HRX; HTRX; KMT2A; MLL1; TRX1; ALL-1; CXXC-type zinc finger protein 7; Lysine N-methyltransferase 2A; Trithorax-like protein; Zinc finger protein HRX; anti-MLL antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Specificity
MLL Monoclonal Antibody detects endogenous levels of MLL protein.
Purity/Purification
Affinity purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-MLL antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Purified recombinant fragment of MLL (aa3751-3968) expressed in E coli.
Modification
Unmodified/Total
Preparation and Storage
Store at -20 degree C/1 year
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human lung cancer (left) and esophagus cancer (right). showing nuclear localization with DAB staining using MLL Monoclonal Antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human lung cancer (left) and esophagus cancer (right). showing nuclear localization with DAB staining using MLL Monoclonal Antibody.)
WB (Western Blot)
(Western Blot analysis using MLL Monoclonal Antibody against truncated MLL recombinant protein (1) and truncated GFP-MLL(aa3714-3969) transfected Cos7 cell lysate (2).)
WB (Western Blot)
(Western Blot analysis using MLL Monoclonal Antibody against truncated MLL recombinant protein (1) and truncated GFP-MLL(aa3714-3969) transfected Cos7 cell lysate (2).)
Related Product Information for anti-MLL antibody
This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefS
Product Categories/Family for anti-MLL antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
3969
NCBI Official Full Name
Histone-lysine N-methyltransferase 2A
NCBI Official Synonym Full Names
lysine (K)-specific methyltransferase 2A
NCBI Official Symbol
KMT2A
NCBI Official Synonym Symbols
HRX; MLL; MLL1; TRX1; ALL-1; CXXC7; HTRX1; MLL1A; WDSTS; MLL/GAS7; TET1-MLL
NCBI Protein Information
histone-lysine N-methyltransferase 2A; trithorax-like protein; CDK6/MLL fusion protein; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; zinc finger protein HRX; mixed lineage leukemia 1; MLL-AF4 der(11) fusion protein; CXXC-type zinc finger protein 7; m
UniProt Protein Name
Histone-lysine N-methyltransferase 2A
UniProt Gene Name
KMT2A
UniProt Synonym Gene Names
ALL1; CXXC7; HRX; HTRX; MLL; MLL1; TRX1; Lysine N-methyltransferase 2A; p320; p180
UniProt Entry Name
KMT2A_HUMAN
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Product Notes
The MLL kmt2a (Catalog #AAA320159) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MLL Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLL can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MLL kmt2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLL, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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