WB (Western Blot)
(Anti-MLL3 Antibody at 1:2000 dilution + Recombinant proteinLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 541 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Mouse anti-Human MLL3 Monoclonal Antibody | anti-KMT2C antibody
MLL3 Antibody
Gene Names
KMT2C; HALR; MLL3
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified Mouse Monoclonal Antibody (Mab)
Synonyms
MLL3, Antibody; MLL3 Antibody; Histone-lysine N-methyltransferase 2C; Lysine N-methyltransferase 2C; 2.1.1.43; Homologous to ALR protein; Myeloid/lymphoid or mixed-lineage leukemia protein 3; KMT2C; HALR; KIAA1506; MLL3; anti-KMT2C antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1686CT202.60.69
Specificity
This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3.
Purity/Purification
Purified Mouse Monoclonal Antibody (Mab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Sequence Length
4911
Applicable Applications for anti-KMT2C antibody
ELISA, WB (Western Blot)
Cellular Location
Nucleus.
Tissue Location
Highly expressed in testis and ovary, followed by brain and liver. Also expressed in placenta, peripherical blood, fetal thymus, heart, lung and kidney. Within brain, expression was highest in hippocampus, caudate nucleus, and substantia nigra. Not detected in skeletal muscle and fetal liver.
Antigen Type
Recombinant Protein
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Anti-MLL3 Antibody at 1:2000 dilution + Recombinant proteinLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 541 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-MLL3 Antibody at 1:2000 dilution + Recombinant proteinLysates/proteins at 20 ug per lane.SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 541 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-KMT2C antibody
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
References
Ruault M.,et al.Gene 284:73-81 (2002). Tan Y.C.,et al.Cancer Detect. Prev. 25:454-469 (2001). Hillier L.W.,et al.Nature 424:157-164 (2003). Nagase T.,et al.DNA Res. 7:143-150 (2000). Nakajima D.,et al.DNA Res. 9:99-106 (2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
histone-lysine N-methyltransferase 2C
NCBI Official Synonym Full Names
lysine methyltransferase 2C
NCBI Official Symbol
KMT2C
NCBI Official Synonym Symbols
HALR; MLL3
NCBI Protein Information
histone-lysine N-methyltransferase 2C
UniProt Protein Name
Histone-lysine N-methyltransferase 2C
UniProt Gene Name
KMT2C
UniProt Synonym Gene Names
HALR; KIAA1506; MLL3; Lysine N-methyltransferase 2C
UniProt Entry Name
KMT2C_HUMAN
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Product Notes
The KMT2C kmt2c (Catalog #AAA290649) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MLL3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLL3 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KMT2C kmt2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLL3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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