WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MMACHC protein (Right) or empty vector (Left) detected with MMACHC antibody)
Mouse MMACHC Monoclonal Antibody | anti-MMACHC antibody
MMACHC antibody
Gene Names
MMACHC; cblC
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
MMACHC antibody was purified by affinity chromatography.
Synonyms
MMACHC, Antibody; MMACHC antibody; Monoclonal MMACHC; Anti-MMACHC; cblC; DKFZp564I122; FLJ25671; RP11-291L19.3; anti-MMACHC antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E9
Purity/Purification
MMACHC antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
0.5-1 mg/ml (varies by lot)
Sequence Length
282
Applicable Applications for anti-MMACHC antibody
WB (Western Blot), FCM/FACS (Flow Cytometry)
Biological Significance
The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Cross-Reactivity
Human
Immunogen
MMACHC antibody was raised in Mouse using full length human recombinant protein of human MMACHC produced in HEK293T cell as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MMACHC protein (Right) or empty vector (Left) detected with MMACHC antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MMACHC protein (Right) or empty vector (Left) detected with MMACHC antibody)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of HEK293T cells transfected with either recombinant MMACHC protein (red) or empty vector (blue) stained using MMACHC antibody)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of HEK293T cells transfected with either recombinant MMACHC protein (red) or empty vector (blue) stained using MMACHC antibody)
Related Product Information for anti-MMACHC antibody
Mouse monoclonal MMACHC antibody
Product Categories/Family for anti-MMACHC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,728 Da
NCBI Official Full Name
methylmalonic aciduria and homocystinuria type C protein
NCBI Official Synonym Full Names
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
NCBI Official Symbol
MMACHC
NCBI Official Synonym Symbols
cblC
NCBI Protein Information
methylmalonic aciduria and homocystinuria type C protein
UniProt Protein Name
Methylmalonic aciduria and homocystinuria type C protein
UniProt Gene Name
MMACHC
UniProt Entry Name
MMAC_HUMAN
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Product Notes
The MMACHC mmachc (Catalog #AAA107200) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MMACHC can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the MMACHC mmachc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMACHC, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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