SDS-PAGE
(SDS-PAGE Analysis of Purified MMP3 Rabbit Recombinant Monoclonal Antibody (MMP3/1994R).)
Rabbit MMP3 Monoclonal Antibody | anti-MMP3 antibody
MMP3
Gene Names
MMP3; SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
Reactivity
Human. Others not tested.
Applications
Immunohistochemistry
Synonyms
MMP3, Antibody; MMP3; CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1; anti-MMP3 antibody
Host
Rabbit
Reactivity
Human. Others not tested.
Clonality
Monoclonal
Isotype
IgG
Clone Number
MMP3/1994R
Specificity
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
Form/Format
200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
477
Applicable Applications for anti-MMP3 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment of human MMP3 protein (around aa 317-327)
Cellular Localization
Cytoplasm, extracellular matrix.
Hu-chromosome Location
11q22.2
Positive Control
Human prostate or lung tissue. A-431 cells.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis of Purified MMP3 Rabbit Recombinant Monoclonal Antibody (MMP3/1994R).)
SDS-PAGE
(SDS-PAGE Analysis of Purified MMP3 Rabbit Recombinant Monoclonal Antibody (MMP3/1994R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human spleen stained with MMP3 Rabbit Recombinant Monoclonal Antibody (MMP3/1994R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human spleen stained with MMP3 Rabbit Recombinant Monoclonal Antibody (MMP3/1994R).)
References
Shur, S.A., et al. 1983. The role of cysteinyl residues in the phosphorylase kinase activity as revealed by iodacetamide modification. Biochem. Int. 7: 197-206
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57kDa
NCBI Official Full Name
stromelysin-1 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 3
NCBI Official Symbol
MMP3
NCBI Official Synonym Symbols
SL-1; STMY; STR1; CHDS6; MMP-3; STMY1
NCBI Protein Information
stromelysin-1
UniProt Protein Name
Stromelysin-1
UniProt Gene Name
MMP3
UniProt Synonym Gene Names
STMY1; SL-1; MMP-3
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Product Notes
The MMP3 mmp3 (Catalog #AAA214449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP3 reacts with Human. Others not tested. and may cross-react with other species as described in the data sheet. AAA Biotech's MMP3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MMP3 mmp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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