IHC (Immunohiostchemistry)
(IHC of MSH6 on an FFPE Colon Adenocarcinoma tissue)
Rabbit anti-Human MSH6 Monoclonal Antibody | anti-MSH6 antibody
MSH6 (RBT-MSH6), RMab
Reactivity
Human
Synonyms
MSH6, Antibody; MSH6 (RBT-MSH6), RMab; MSH6, (RBT-MSH6); TFF3; trefoil factor 3 intestinal; ITF; P1B; TFI; anti-tff3; anti-itf; anti-MSH6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-MSH6
Form/Format
This antibody is derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide.
Localization
Nuclear
Intended Use
MSH6 (RBT-MSH6), rabbit monoclonal antibody, is a primary antibody intended for laboratory use by trained laboratory personnel in an immunohistochemical (IHC) assay to qualitatively identify the MSH6 protein by light microscopy in normal and/or pathological formalin-fixed, paraffin-embedded (FFPE) human tissue. The clinical interpretation of any staining or its absence should beperformed by a qualified pathologist and complemented by morphological studies using proper controls and evaluated within the context of the patient’s clinical history and other tests.
IHC (Immunohiostchemistry)
(IHC of MSH6 on an FFPE Colon Adenocarcinoma tissue)
IHC (Immunohiostchemistry)
(IHC of MSH6 on an FFPE Colon Adenocarcinoma tissue)
Dilution Info
Dilution Info
Related Product Information for anti-MSH6 antibody
MSH6, also known as mutS homolog 6, is a gene commonly associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset Colorectal Carcinoma and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited Colorectal Cancer in the western world. MSH6 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H). The anti-MSH6 antibody is useful in screening patients and families for HNPCC. Colon cancers that are microsatellite-unstable have a better prognosis than their microsatellite-stable counterpart.
Similar Products
Product Notes
The MSH6 (Catalog #AAA59494) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MSH6 (RBT-MSH6), RMab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "MSH6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.