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product-image-AAA311016_ICC8.jpg ICC (Immunocytochemistry) (ICC staining MSK1 (phospho S376) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

Rabbit MSK1 Monoclonal Antibody | anti-MSK1 antibody

MSK1 (Phospho-phospho S376) Antibody

Gene Names
RPS6KA5; MSK1; RLPK; MSPK1
Reactivity
Human, Mouse, Rat
Applications
Immunoprecipitation, Immunohistochemistry, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
MSK1, Antibody; MSK1 (Phospho-phospho S376) Antibody; 90 kDa ribosomal protein S6 kinase 5 antibody; EC 2.7.11.1 antibody; KS6A5_HUMAN antibody; MGC1911 antibody; Mitogen and stress activated protein kinase 1 antibody; MSPK1 antibody; Nuclear Mitogen And Stress Activated Protein Kinase 1 antibody; Nuclear mitogen- and stress-activated protein kinase 1 antibody; Ribosomal protein S6 kinase 90kD polypeptide 5 antibody; Ribosomal protein S6 kinase 90kDa antibody; Ribosomal protein S6 kinase 90kDa polypeptide 5 antibody; Ribosomal Protein S6 Kinase Alpha 5 antibody; Ribosomal protein S6 kinase alpha-5 antibody; RLPK antibody; RPS6KA5 antibody; RSK Like Protein Kinase antibody; RSK-like protein kinase antibody; RSKL antibody; S6K alpha 5 antibody; S6K-alpha-5 antibody; anti-MSK1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
SN63-05
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-MSK1 antibody
IP (Immunoprecipitation), IHC (Immunohistochemistry), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser376 of human MSK1.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

ICC (Immunocytochemistry)

(ICC staining MSK1 (phospho S376) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA311016_ICC8.jpg ICC (Immunocytochemistry) (ICC staining MSK1 (phospho S376) in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining MSK1 (phospho S376) in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA311016_ICC10.jpg ICC (Immunocytochemistry) (ICC staining MSK1 (phospho S376) in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining MSK1 (phospho S376) in LO2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA311016_ICC11.jpg ICC (Immunocytochemistry) (ICC staining MSK1 (phospho S376) in LO2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining MSK1 (phospho S376) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

product-image-AAA311016_ICC13.jpg ICC (Immunocytochemistry) (ICC staining MSK1 (phospho S376) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded mouse bladder tissue using anti-MSK1 (phospho S376) antibody. Counter stained with hematoxylin.)

product-image-AAA311016_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded mouse bladder tissue using anti-MSK1 (phospho S376) antibody. Counter stained with hematoxylin.)
Related Product Information for anti-MSK1 antibody
The family of ribosomal S6 kinases (Rsks), designated Rsk-1, Rsk-2 and Rsk-3, have been implicated as important signaling intermediates in response to a broad range of ligand-activated receptor tyrosine kinases. A unique feature common to the three members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. A related S6 kinase, p70 S6 kinase, functions to phosphorylate the S6 protein on ribosomal 40S subunits. p70 S6 kinase b shares high sequence homology with p70 S6 kinase, except in the carboxy terminus where it contains a proline-rich domain that may be involved in SH3 domain containing protein interactions. MSK1 (also designated RLPK) is related to Rsk and p70 S6 kinase family members and is thought to be structurally similar to Rsk family members, but it may be regulated by distinct mechanisms.
Product Categories/Family for anti-MSK1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
89,865 Da
NCBI Official Full Name
ribosomal protein S6 kinase alpha-5 isoform a
NCBI Official Synonym Full Names
ribosomal protein S6 kinase, 90kDa, polypeptide 5
NCBI Official Symbol
RPS6KA5
NCBI Official Synonym Symbols
MSK1; RLPK; MSPK1
NCBI Protein Information
ribosomal protein S6 kinase alpha-5; RSKL; S6K-alpha-5; RSK-like protein kinase; 90 kDa ribosomal protein S6 kinase 5; nuclear mitogen- and stress-activated protein kinase 1
UniProt Protein Name
Ribosomal protein S6 kinase alpha-5
UniProt Gene Name
RPS6KA5
UniProt Synonym Gene Names
MSK1; S6K-alpha-5; RSKL
UniProt Entry Name
KS6A5_HUMAN

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Product Notes

The MSK1 rps6ka5 (Catalog #AAA311016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MSK1 (Phospho-phospho S376) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MSK1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IHC (Immunohistochemistry), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MSK1 rps6ka5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSK1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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