WB (Western Blot)
(Western blot analysis of MyD88 in EL4 whole cell lysate with MyD88 antibody at 2 ug/mL.)
Mouse anti-Human, Mouse MyD88 Monoclonal Antibody | anti-MyD88 antibody
MyD88 Monoclonal Antibody
Gene Names
MYD88; MYD88D
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity chromotography purified IgG
Synonyms
MyD88, Antibody; MyD88 Monoclonal Antibody; MyD88 (2E9C2): Myeloid differentiation primary response gene 88; anti-MyD88 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Clone Number
2E9C2
Purity/Purification
Immunoaffinity chromotography purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
296
Applicable Applications for anti-MyD88 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Recombinant protein
Immunogen Description
Raised against a recombinant protein corresponding to amino acids 176 to 280 of human MyD88.
Target Name
MyD88
Preparation and Storage
Can be stored at -20 degree C, stable for one year.
WB (Western Blot)
(Western blot analysis of MyD88 in EL4 whole cell lysate with MyD88 antibody at 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of MyD88 in EL4 whole cell lysate with MyD88 antibody at 2 ug/mL.)
Related Product Information for anti-MyD88 antibody
The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. MyD88 has been identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.
Product Categories/Family for anti-MyD88 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,097 Da
NCBI Official Full Name
MyD88
NCBI Official Synonym Full Names
myeloid differentiation primary response 88
NCBI Official Symbol
MYD88
NCBI Official Synonym Symbols
MYD88D
NCBI Protein Information
myeloid differentiation primary response protein MyD88
UniProt Protein Name
Myeloid differentiation primary response protein MyD88
UniProt Gene Name
MYD88
UniProt Entry Name
MYD88_HUMAN
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Product Notes
The MyD88 myd88 (Catalog #AAA300792) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MyD88 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MyD88 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the MyD88 myd88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MyD88, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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