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product-image-AAA14890_IHC7.jpg IHC (Immunohistochemistry) (Figure-7: Immunohistochemical analysis of Trim29 in Uterus endometrial carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

Mouse anti-Human NALE Trim29 Monoclonal Antibody | anti-Trim29 antibody

NALE Monoclonal Antibody to Trim29 (Clone: ABM43D2)

Gene Names
TRIM29; ATDC
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein G Chromatography
Synonyms
NALE Trim29, Antibody; NALE Monoclonal Antibody to Trim29 (Clone: ABM43D2); TRIM29; ATDC; anti-Trim29 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG2b Kappa
Clone Number
ABM43D2
Purity/Purification
Protein G Chromatography
Form/Format
Azide Free, Purified; 25 ug in 50 ul/100 ug in 200 ul PBS containing no Azide and low endotoxin (0.1 EU/1ug).
Applicable Applications for anti-Trim29 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB: 1-2 ug/ml
IHC: 1 ug/ml
Immunogen
A partial length recombinant Trim29 protein (amino acids 2-291) was used as the immunogen for this antibody.
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles.

IHC (Immunohistochemistry)

(Figure-7: Immunohistochemical analysis of Trim29 in Uterus endometrial carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

product-image-AAA14890_IHC7.jpg IHC (Immunohistochemistry) (Figure-7: Immunohistochemical analysis of Trim29 in Uterus endometrial carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

IHC (Immunohistchemistry)

(Figure-6: Immunohistochemical analysis of Trim29 in Hepatocellular carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

product-image-AAA14890_IHC6.jpg IHC (Immunohistchemistry) (Figure-6: Immunohistochemical analysis of Trim29 in Hepatocellular carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

IHC (Immunohistochemistry)

(Figure-5: Immunohistochemical analysis of Trim29 in Renal cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2) .)

product-image-AAA14890_IHC5.jpg IHC (Immunohistochemistry) (Figure-5: Immunohistochemical analysis of Trim29 in Renal cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2) .)

IHC (Immunohistochemistry)

(Figure-4: Immunohistochemical analysis of Trim29 in Esophagus squamous cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

product-image-AAA14890_IHC4.jpg IHC (Immunohistochemistry) (Figure-4: Immunohistochemical analysis of Trim29 in Esophagus squamous cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

IHC (Immunohistochemistry)

(Figure-3: Immunohistochemical analysis of Trim29 in human Lungs squamous cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

product-image-AAA14890_IHC3.jpg IHC (Immunohistochemistry) (Figure-3: Immunohistochemical analysis of Trim29 in human Lungs squamous cell carcinoma tissue (20X) using Trim29 antibody (Clone: ABM43D2).)

IHC (Immunohistochemistry)

(Fig-2: Immunohistochemical analysis of Trim29  in human lung adenocarcinoma tissue using Trim29 antibody (Clone: ABM43D2) at 1 ug/ml.)

product-image-AAA14890_IHC2.jpg IHC (Immunohistochemistry) (Fig-2: Immunohistochemical analysis of Trim29  in human lung adenocarcinoma tissue using Trim29 antibody (Clone: ABM43D2) at 1 ug/ml.)

WB (Western Blot)

(Fig-1: Western blot analysis of Trim29. Anti- Trim29 antibody (Clone: ABM43D2) was tested at 1 ug/ml Hela lysate.)

product-image-AAA14890_WB.jpg WB (Western Blot) (Fig-1: Western blot analysis of Trim29. Anti- Trim29 antibody (Clone: ABM43D2) was tested at 1 ug/ml Hela lysate.)
Related Product Information for anti-Trim29 antibody
TRIM29 (Tripartite motif-containing 29) is a member of the tripartite motif (TRIM) family of transcription factors, characterized by the conserved RING finger, B-box, and coiled-coil domains. The TRIM family has been implicated in a variety of physiologic processes including development, apoptosis and epithelial-mesenchymal transition (EMT). Depending on a tumor types, TRIM29 also may function as an oncogene or a tumor suppressor. As an oncogene, it facilitates tumor cell proliferation and invasion through stabilization of Beta-catenin. The mechanisms may also involve deactivation of p53 activity and promoting cell survival by inhibiting proapoptotic genes regulated by p53. As a histone binding protein TRIM29 is responsible for DDR (DNA damage response). It functions as a scaffold protein to assemble DNA repair proteins into chromatin followed by efficient activation of DDR. TRIM29 binds to modified histone H3 and H4 tails in the context of nucleosomes. Furthermore, chromatin binding of TRIM29 is required for the phosphorylation of H2AX nucleosomes and cell viability in response to ionizing radiation.
Product Categories/Family for anti-Trim29 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
588
NCBI Official Full Name
Tripartite motif-containing protein 29
NCBI Official Synonym Full Names
tripartite motif containing 29
NCBI Official Symbol
TRIM29
NCBI Official Synonym Symbols
ATDC
NCBI Protein Information
tripartite motif-containing protein 29; tripartite motif-containing 29; tripartite motif protein TRIM29; ataxia telangiectasia group D-associated protein; ataxia-telangiectasia group D-associated protein
UniProt Protein Name
Tripartite motif-containing protein 29
UniProt Gene Name
TRIM29
UniProt Synonym Gene Names
ATDC
UniProt Entry Name
TRI29_HUMAN

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Product Notes

The Trim29 trim29 (Catalog #AAA14890) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NALE Monoclonal Antibody to Trim29 (Clone: ABM43D2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NALE Trim29 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). WB: 1-2 ug/ml IHC: 1 ug/ml. Researchers should empirically determine the suitability of the Trim29 trim29 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NALE Trim29, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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