Mouse anti-Human NFkappaB-p105/p50 Monoclonal Antibody | anti-NFkappaB-p105/p50 antibody

NFkappaB-p105/p50 Monoclonal Antibody

Cat. Num. AAA320176

• Gene Names: NFKB1; p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
• Reactivity: Human
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: NFkappaB-p105/p50, Antibody; NFkappaB-p105/p50 Monoclonal Antibody; Nuclear factor NF-kappa-B p108 subunit; NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; anti-NFkappaB-p105/p50 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: NFkappaB-p105/p50 Monoclonal Antibody detects endogenous levels of NFkappaB-p105/p50 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-NFkappaB-p105/p50 antibody: ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human NFkappaB-p105/p50 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

Application Data

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of MCF-7 cells using NF?B-p105/p50 Monoclonal Antibody (green) and negative control (purple).)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded prostate tissues (left) and bladder cancer tissues (right) with DAB staining using NF?B-p105/p50 Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using NF?B-p105/p50 Monoclonal Antibody against K562 (1). Jurkat (2). A431 (3). HeLa (4). THP-1 (5) and MCF-7 (6) cell lysate.)

Related Product Information for anti-NFkappaB-p105/p50 antibody

nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals,ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

Product Categories/Family for anti-NFkappaB-p105/p50 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 259155302
• NCBI GeneID: 4790
• NCBI Accession #: NP_001158884.1
• NCBI GenBank Nucleotide #: NM_001165412.1
• UniProt Accession #: P19838; Q68D84; Q86V43; Q8N4X7; Q9NZC0; A8K5Y5; B3KVE8
• Molecular Weight: 105,356 Da
• NCBI Official Full Name: nuclear factor NF-kappa-B p105 subunit isoform 2
• NCBI Official Synonym Full Names: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• NCBI Official Symbol: NFKB1
• NCBI Official Synonym Symbols: p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
• NCBI Protein Information: nuclear factor NF-kappa-B p105 subunit; NF-kappabeta; DNA binding factor KBF1; DNA-binding factor KBF1; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B DNA binding subunit
• UniProt Protein Name: Nuclear factor NF-kappa-B p105 subunit
• UniProt Gene Name: NFKB1
• UniProt Entry Name: NFKB1_HUMAN