IHC (Immunohiostchemistry)
(Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 antibody at 2.5 ug/mL.)
Mouse ORAI1 Monoclonal Antibody | anti-ORAI1 antibody
ORAI1 Monoclonal Antibody
Gene Names
ORAI1; IMD9; TAM2; ORAT1; CRACM1; TMEM142A
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity chromotography purified IgG
Synonyms
ORAI1, Antibody; ORAI1 Monoclonal Antibody; ORAI1 (6D11A11), Transmembrane protein 142A, TMEM142A, Calcium release-activated calcium channel protein 1; anti-ORAI1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
6D11A11
Purity/Purification
Immunoaffinity chromotography purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
287
Applicable Applications for anti-ORAI1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide from near the carboxy terminus of human ORAI1.
Target Name
ORAI1
Preparation and Storage
Can be stored at -20 degree C, stable for one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of ORAI1 in human spleen tissue lysate with ORAI1 antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of ORAI1 in human spleen tissue lysate with ORAI1 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-ORAI1 antibody
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one fo rm of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
Product Categories/Family for anti-ORAI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
25,337 Da
NCBI Official Full Name
ORAI1 protein, partial
NCBI Official Synonym Full Names
ORAI calcium release-activated calcium modulator 1
NCBI Official Symbol
ORAI1
NCBI Official Synonym Symbols
IMD9; TAM2; ORAT1; CRACM1; TMEM142A
NCBI Protein Information
calcium release-activated calcium channel protein 1
UniProt Protein Name
Calcium release-activated calcium channel protein 1
UniProt Gene Name
ORAI1
UniProt Synonym Gene Names
CRACM1; TMEM142A
UniProt Entry Name
CRCM1_HUMAN
Similar Products
ORAI1 Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: Immunohistochemistry, Western Blot, ELISA
ORAI1 Antibody
Host: Rabbit
Reactivity: Human, Mouse
Apps: Immunohistochemistry, Western Blot, ELISA
Product Notes
The ORAI1 orai1 (Catalog #AAA300778) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ORAI1 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ORAI1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ORAI1 orai1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ORAI1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.