Application Data
Mouse Otoferlin Monoclonal Antibody | anti-Otof antibody
Otoferlin Monoclonal Antibody
Applications
Immunofluorescence, Immunoblot, Western Blot
Synonyms
Otoferlin, Antibody; Otoferlin Monoclonal Antibody; Anti-Otoferlin; anti-Otof antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes human otoferlin.
Form/Format
100ug, Protein A-purified, lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
Sequence Length
1998
Applicable Applications for anti-Otof antibody
IF (Immunofluorescence), IB (Immunoblot)
Antigen
GST fusion protein corresponding to aa 1-395 of human otoferlin (accession no. Q9HC10).
Reconstitution
Reconstitute in distilled water.
Preparation and Storage
This product is stable for at least one year at -20°C to -70°C. Reconstited product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
Application Data
Application Data
Related Product Information for anti-Otof antibody
Otoferlin protein is the product of the OTOF gene. Otoferlin is present in the brain and the cochlea of the inner ear where sound is processed. Hearing relies on Ca2+ influx-driven exocytosis of synaptic vesicles at the ribbon-type active zones of hair cells. The presence of several C2 domains in otoferlin, some of which bind Ca2+, suggest that otoferlin is a Ca2+ sensor for fusion in inner hair cell (IHC) synapses.
Product Categories/Family for anti-Otof antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
226,339 Da
NCBI Official Full Name
otoferlin
NCBI Official Synonym Full Names
otoferlin
NCBI Official Symbol
Otof
NCBI Protein Information
otoferlin
UniProt Protein Name
Otoferlin
UniProt Gene Name
Otof
UniProt Synonym Gene Names
Fer1l2
UniProt Entry Name
OTOF_RAT
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Product Notes
The Otof otof (Catalog #AAA47774) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Otoferlin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IB (Immunoblot). Researchers should empirically determine the suitability of the Otof otof for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Otoferlin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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