Mouse anti-Human OTX2 Monoclonal Antibody | anti-OTX2 antibody

OTX2 Monoclonal Antibody

Cat. Num. AAA320185

• Gene Names: OTX2; CPHD6; MCOPS5
• Reactivity: Human
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: OTX2, Antibody; OTX2 Monoclonal Antibody; Homeobox protein OTX2; OTX2; Orthodenticle homolog 2; anti-OTX2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: OTX2 Monoclonal Antibody detects endogenous levels of OTX2 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-OTX2 antibody: ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human OTX2 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

Application Data

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of HepG2 cells using OTX2 Monoclonal Antibody (green) and negative control (purple).)

IF (Immunofluorescence)

(Immunofluorescence analysis of HepG2 cells using OTX2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded prostate tissues (left) and colon cancer tissues (right) with DAB staining using OTX2 Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using OTX2 Monoclonal Antibody against HepG2 (1). Jurkat (2). and NTERA-2 (3) cell lysate.)

Related Product Information for anti-OTX2 antibody

This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]

Product Categories/Family for anti-OTX2 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 395455071
• NCBI GeneID: 5015
• NCBI Accession #: NP_001257452.1
• NCBI GenBank Nucleotide #: NM_001270523.1
• UniProt Accession #: P32243; Q6GTV3; Q9HAW3; Q9P2R1; B2RAN5
• Molecular Weight: 32,406 Da
• NCBI Official Full Name: homeobox protein OTX2 isoform b
• NCBI Official Synonym Full Names: orthodenticle homeobox 2
• NCBI Official Symbol: OTX2
• NCBI Official Synonym Symbols: CPHD6; MCOPS5
• NCBI Protein Information: homeobox protein OTX2
• UniProt Protein Name: Homeobox protein OTX2
• UniProt Gene Name: OTX2
• UniProt Entry Name: OTX2_HUMAN