IHC (Immunohiostchemistry)
(OTX2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit OTX2 Polyclonal Antibody | anti-OTX2 antibody
OTX2 Antibody (C-term)
Gene Names
OTX2; CPHD6; MCOPS5
Reactivity
Human, mouse (Predicted Reactivity: Xenopus, Zebrafish)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
OTX2, Antibody; OTX2 Antibody (C-term); Homeobox protein OTX2; Orthodenticle homolog 2; OTX2; anti-OTX2 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Xenopus, Zebrafish)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.26 (varies by lot)
Sequence Positions
261-289
Sequence Length
297
Applicable Applications for anti-OTX2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(OTX2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(OTX2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTX2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(OTX2 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the OTX2 antibody detected the OTX2 protein (arrow).)
WB (Western Blot)
(OTX2 Antibody (C-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the OTX2 antibody detected the OTX2 protein (arrow).)
Related Product Information for anti-OTX2 antibody
This gene encodes a member of the bicoid sub-family of
homeodomain-containing transcription factors. The encoded protein
acts as a transcription factor and may play a role in brain and
sensory organ development. A similar protein in mice is required
for proper forebrain development. Two transcript variants encoding
distinct isoforms have been identified for this gene. Other
alternative splice variants may exist, but their full length
sequences have not been determined.
homeodomain-containing transcription factors. The encoded protein
acts as a transcription factor and may play a role in brain and
sensory organ development. A similar protein in mice is required
for proper forebrain development. Two transcript variants encoding
distinct isoforms have been identified for this gene. Other
alternative splice variants may exist, but their full length
sequences have not been determined.
Product Categories/Family for anti-OTX2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)
Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)
Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :
Ashkenazi-Hoffnung, L., et al. Hum. Genet. 127(6):721-729(2010)
Masuda, T., et al. J. Biol. Chem. 285(35):26933-26944(2010)
Gonzalez-Rodriguez, J., et al. Br J Ophthalmol 94(8):1100-1104(2010)
Chung, C.Y., et al. Brain 133 (PT 7), 2022-2031 (2010) :
Ashkenazi-Hoffnung, L., et al. Hum. Genet. 127(6):721-729(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31636
NCBI Official Full Name
homeobox protein OTX2 isoform b
NCBI Official Synonym Full Names
orthodenticle homeobox 2
NCBI Official Symbol
OTX2
NCBI Official Synonym Symbols
CPHD6; MCOPS5
NCBI Protein Information
homeobox protein OTX2
UniProt Protein Name
Homeobox protein OTX2
UniProt Gene Name
OTX2
UniProt Entry Name
OTX2_HUMAN
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Product Notes
The OTX2 otx2 (Catalog #AAA287913) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 261-289. The OTX2 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Xenopus, Zebrafish) and may cross-react with other species as described in the data sheet. AAA Biotech's OTX2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the OTX2 otx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OTX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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