IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human colon. CTNND1/4383R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
Rabbit anti-Human p120/Catenin, delta-1 (CTNND1) Monoclonal Antibody | anti-CTNND1 antibody
p120/Catenin, delta-1 (CTNND1) Recombinant Rabbit Monoclonal Antibody [Clone CTNND1/4383R]
Gene Names
CTNND1; CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
p120/Catenin, delta-1 (CTNND1), Antibody; p120/Catenin, delta-1 (CTNND1) Recombinant Rabbit Monoclonal Antibody [Clone CTNND1/4383R]; Cadherin-associated Src substrate (CAS); Catenin (cadherin associated protein) delta 1; Catenin delta-1; CTNND1; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN; anti-CTNND1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
CTNND1/4383R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CTNND1 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant fragment (around aa900-1,000) of human CTNND1 protein (exact sequence is proprietary)
Cellular Localization
Cell Surface, Cytoplasm
Positive Control
Human colon tissue.
Hu-chromosome Location
11q11
Unigene
166011
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human colon. CTNND1/4383R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
IHC (Immunohistochemistry)
(IHC analysis of formalin-fixed, paraffin-embedded human colon. CTNND1/4383R at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9. 0, 45min. 2 degree : HRP-polymer, 30min. DAB, 5min.)
Related Product Information for anti-CTNND1 antibody
Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, p120 catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins. p120 is a proliferation-associated nucleolar protein found in most human malignant tumors, but not in resting normal cells. In colorectal cancer the altered localization of p120 catenin corresponds with loss of cytoplasmic localization of E-cadherin. Studies have shown accurate categorization of ductal vs. lobular neoplasia in the breast was achieved with p120 staining. p120 expression further clarifies the separation of low-grade ductal carcinoma in situ from lobular neoplasia. Studies also have shown that altered expression of p120 catenin antibody predicts poor outcome in invasive breast cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
108,170 Da
NCBI Official Full Name
catenin delta-1 isoform 1ABC
NCBI Official Synonym Full Names
catenin (cadherin-associated protein), delta 1
NCBI Official Symbol
CTNND1
NCBI Official Synonym Symbols
CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
NCBI Protein Information
catenin delta-1; p120 catenin; cadherin-associated Src substrate
UniProt Protein Name
Catenin delta-1
UniProt Gene Name
CTNND1
UniProt Synonym Gene Names
KIAA0384; CAS; p120(ctn)
UniProt Entry Name
CTND1_HUMAN
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Product Notes
The CTNND1 ctnnd1 (Catalog #AAA215583) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p120/Catenin, delta-1 (CTNND1) Recombinant Rabbit Monoclonal Antibody [Clone CTNND1/4383R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p120/Catenin, delta-1 (CTNND1) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CTNND1 ctnnd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p120/Catenin, delta-1 (CTNND1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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