Mouse PGP9. 5/UchL1 Monoclonal Antibody | anti-UCHL1 antibody

PGP9.5/UchL1 (pan-Neuronal Marker) Recombinant Mouse Monoclonal Antibody [Clone rUCHL1/4557]

Cat. Num. AAA215975

• Gene Names: UCHL1; PARK5; PGP95; PGP9.5; Uch-L1; PGP 9.5
• Reactivity: Human, Dog and Rat. Shows a broad species reactivity.
• Applications: Immunohistochemistry, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
• Synonyms: PGP9. 5/UchL1, Antibody; PGP9.5/UchL1 (pan-Neuronal Marker) Recombinant Mouse Monoclonal Antibody [Clone rUCHL1/4557]; PGP9. 5/UchL1 (pan-Neuronal Marker); Gracile Axonal Dystrophy; Neuron Cytoplasmic Protein 9. 5; Park5; Parkinson Disease 5; PGP95; Protein Gene Product 9. 5; Ubiquitin Carboxyl-terminal Esterase L1; Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1; Ubiquitin Thioesterase L1; Ubiquitin Thiolesterase L1; anti-UCHL1 antibody

• Host: Mouse
• Reactivity: Human, Dog and Rat. Shows a broad species reactivity.
• Clonality: Monoclonal
• Isotype: Mouse/IgG2a, kappa
• Clone Number: rUCHL1/4557
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml; OR; Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)

• Applicable Applications for anti-UCHL1 antibody: IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant full-length human UCHL1 protein
• Cellular Localization: Cytoplasmic, Endoplasmic reticulum membrane
• Positive Control: Cerebellum
• Hu-chromosome Location: 4p13
• Unigene: 518731
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C; Antibody without azide: store at -20 to -80 degree C; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human cerebellum stained with Pgp9. 5 Mouse Recombinant Monoclonal Antibody (rUCHL1/4557).)

Related Product Information for anti-UCHL1 antibody

This MAb reacts with a protein of 20-30kDa, identified as PGP9. 5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9. 5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9. 5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9. 5 gene is believed to cause a form of Parkinson's disease.

NCBI and Uniprot Product Information

• NCBI GI #: 21361091
• NCBI GeneID: 7345
• NCBI Accession #: NP_004172.2
• NCBI GenBank Nucleotide #: NM_004181.4
• UniProt Accession #: P09936; Q4W5K6; Q71UM0
• Molecular Weight: 24,824 Da
• NCBI Official Full Name: ubiquitin carboxyl-terminal hydrolase isozyme L1
• NCBI Official Synonym Full Names: ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• NCBI Official Symbol: UCHL1
• NCBI Official Synonym Symbols: PARK5; PGP95; PGP9.5; Uch-L1; PGP 9.5
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thioesterase L1; neuron cytoplasmic protein 9.5; ubiquitin C-terminal hydrolase
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase isozyme L1
• UniProt Gene Name: UCHL1
• UniProt Synonym Gene Names: UCH-L1; PGP9.5
• UniProt Entry Name: UCHL1_HUMAN