WB (Western Blot)
(Western blot of extracts from 293 cells, using PGP9.5 Antibody. The lane on the right is treated with the synthesized peptide.)
Rabbit UCHL1 / PGP9.5 Polyclonal Antibody | anti-UCHL1 antibody
Rabbit Polyclonal (IgG) to Human UCHL1 / PGP9.5
Gene Names
UCHL1; NDGOA; PARK5; PGP95; PGP9.5; Uch-L1; HEL-117; PGP 9.5
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
UCHL1 / PGP9.5, Antibody; Rabbit Polyclonal (IgG) to Human UCHL1 / PGP9.5; Anti-UCHL1 / PGP9.5 Antibody (aa171-220) IHC-plus; UCHL1; Ubiquitin C-terminal hydrolase; PARK5; PGP9.5; PGP95; Ubiquitin thioesterase L1; Neuron cytoplasmic protein 9.5; PGP 9.5; Uch-L1; Human UCHL1; anti-UCHL1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
223
Applicable Applications for anti-UCHL1 antibody
ELISA, WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide from human PGP9.5 (aa171-220).
Immunogen
UCHL1 / PGP9.5 antibody was raised against synthetic peptide from human PGP9.5 (aa171-220).
Antigen Modification
aa171-220
Preparation and Storage
Store at -20 degree C.
WB (Western Blot)
(Western blot of extracts from 293 cells, using PGP9.5 Antibody. The lane on the right is treated with the synthesized peptide.)
WB (Western Blot)
(Western blot of extracts from 293 cells, using PGP9.5 Antibody. The lane on the right is treated with the synthesized peptide.)
IHC (Immunohiostchemistry)
(Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohiostchemistry)
(Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-UCHL1 antibody
UCHL1 is a member of family of proteins that hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. The expression of UCHL1 is highly specific to neurons and to cell of the diffuse neuroendocrine system and their tumors. UCHL1 exhibits both and hydrolase and a ligase activity. The S18Y variant of UCHL1, that has reduced ligase activity, has been linked to susceptibility for Parkinson's disease.
Product Categories/Family for anti-UCHL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24,824 Da
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase isozyme L1
NCBI Official Synonym Full Names
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
NCBI Official Symbol
UCHL1
NCBI Official Synonym Symbols
NDGOA; PARK5; PGP95; PGP9.5; Uch-L1; HEL-117; PGP 9.5
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thioesterase L1; epididymis luminal protein 117; neuron cytoplasmic protein 9.5; ubiquitin C-terminal hydrolase
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
UniProt Gene Name
UCHL1
UniProt Synonym Gene Names
UCH-L1; PGP9.5
UniProt Entry Name
UCHL1_HUMAN
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Product Notes
The UCHL1 uchl1 (Catalog #AAA51342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human UCHL1 / PGP9.5 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UCHL1 / PGP9.5 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the UCHL1 uchl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UCHL1 / PGP9.5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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