Application Data
(All lanes : Anti- at 1:1000 dilution Lane 1: C6 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: mouse cerebellum lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-mouse IgM, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST)
Mouse PIp1 Monoclonal Antibody | anti-Plp1 antibody
Rat PIp1 Antibody (Center)
Gene Names
Plp1; Plp
Reactivity
Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Pig, Rabbit)
Applications
ELISA, Western Blot
Synonyms
PIp1, Antibody; Rat PIp1 Antibody (Center); Myelin proteolipid protein; PLP; Lipophilin; Plp1; Plp; anti-Plp1 antibody
Host
Mouse
Reactivity
Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Pig, Rabbit)
Clonality
Monoclonal
Isotype
IgM
Specificity
This Rat PIp1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 248-277 amino acids from the Central region of rat PIp1.
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Sequence Positions
248-277
Sequence Length
277
Applicable Applications for anti-Plp1 antibody
ELISA, WB (Western Blot)
Cellular Location
Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt- Lanterman incisures of myelin
sheat.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application Data
(All lanes : Anti- at 1:1000 dilution Lane 1: C6 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: mouse cerebellum lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-mouse IgM, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST)
Application Data
(All lanes : Anti- at 1:1000 dilution Lane 1: C6 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: mouse cerebellum lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-mouse IgM, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 30 kDa Blocking/Dilution buffer: 5% NFDM/TBST)
WB (Western Blot)
(RAT PIp1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the PIp1 antibody detected the PIp1 protein (arrow).)
WB (Western Blot)
(RAT PIp1 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the PIp1 antibody detected the PIp1 protein (arrow).)
WB (Western Blot)
(RAT PIp1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PIp1 antibody detected the PIp1 protein (arrow).)
WB (Western Blot)
(RAT PIp1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PIp1 antibody detected the PIp1 protein (arrow).)
Related Product Information for anti-Plp1 antibody
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
References
Mayer, C.A., et al. Respir Physiol Neurobiol 169(3):303-314(2009)
Wang, E., et al. J. Cell. Biochem. 97(5):999-1016(2006)
Gudz, T.I., et al. J. Neurosci. 22(17):7398-7407(2002)
Boucher, S.E., et al. J. Neurosci. 22(5):1772-1783(2002)
Yamamoto, T., et al. Hum. Mutat. 14 (2), 182 (1999) :
Wang, E., et al. J. Cell. Biochem. 97(5):999-1016(2006)
Gudz, T.I., et al. J. Neurosci. 22(17):7398-7407(2002)
Boucher, S.E., et al. J. Neurosci. 22(5):1772-1783(2002)
Yamamoto, T., et al. Hum. Mutat. 14 (2), 182 (1999) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30077
NCBI Official Full Name
myelin proteolipid protein
NCBI Official Synonym Full Names
proteolipid protein 1
NCBI Official Symbol
Plp1
NCBI Official Synonym Symbols
Plp
NCBI Protein Information
myelin proteolipid protein
UniProt Protein Name
Myelin proteolipid protein
UniProt Gene Name
Plp1
UniProt Synonym Gene Names
Plp; PLP
UniProt Entry Name
MYPR_RAT
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Product Notes
The Plp1 plp1 (Catalog #AAA283522) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 248-277. The Rat PIp1 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Pig, Rabbit) and may cross-react with other species as described in the data sheet. AAA Biotech's PIp1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the Plp1 plp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIp1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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