IHC (Immunohistochemisry)
(Immunochemical staining PLP1 in rat brain with rabbit polyclonal antibody (1 ug/mL, formalin-fixed paraffin embedded sections).)
Rabbit PLP1 Polyclonal Antibody | anti-PLP1 antibody
Anti-PLP1 Antibody, Rabbit Polyclonal
Gene Names
PLP1; PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
Reactivity
Human, Mouse, RatPredicted to React with: Cynomolgus (Species predicted to react based on 100% sequence homology)
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
PLP1, Antibody; Anti-PLP1 Antibody, Rabbit Polyclonal; PLP1 Antibody, Rabbit PAb, Antigen Affinity Purified; proteolipid protein 1; Anti-GPM6C Antibody; Anti-HLD1 Antibody; Anti-MMPL Antibody; Anti-PLP Antibody; Anti-PLP/DM20 Antibody; Anti-PMD Antibody; Anti-SPG2 Antibody; anti-PLP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted to React with: Cynomolgus (Species predicted to react based on 100% sequence homology)
Predicted to React with: Cynomolgus (Species predicted to react based on 100% sequence homology)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human PLP1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-PLP1 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide corresponding to the center region of the Human PLP1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human PLP1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
IHC (Immunohistochemisry)
(Immunochemical staining PLP1 in rat brain with rabbit polyclonal antibody (1 ug/mL, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemisry)
(Immunochemical staining PLP1 in rat brain with rabbit polyclonal antibody (1 ug/mL, formalin-fixed paraffin embedded sections).)
IHC (Immunohiostchemistry)
(Immunochemical staining PLP1 in mouse brain with rabbit polyclonal antibody (1 ug/mL, formalin-fixed paraffin embedded sections).)
IHC (Immunohiostchemistry)
(Immunochemical staining PLP1 in mouse brain with rabbit polyclonal antibody (1 ug/mL, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining PLP1 in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining PLP1 in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-PLP1 antibody
The myelin proteolipid protein gene (PLP1) encodes the most abundant protein present in myelin from the central nervous system (CNS). Its expression must be tightly controlled as evidenced by mutations that alter PLP1 dosage; both overexpression (elevated PLP1 copy number) and lack thereof (PLP1 deletion) result in X-linked genetic disorders in man.PLP1 (proteolipid protein1 gene) mutations cause Pelizaeus-Merzbacher disease (PMD), characterized by hypomyelination of the central nervous system, and affecting almost exclusively males. Proteolipid protein 1 gene (PLP1) mutations result in a continuum of neurological findings characterized by X-linked hypomyelinating leukodystrophies of the central nervous system, from mild spastic paraplegia type 2 to severe Pelizaeus-Merzbacher disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
30,077 Da
NCBI Official Full Name
proteolipid protein, partial
NCBI Official Synonym Full Names
proteolipid protein 1
NCBI Official Symbol
PLP1
NCBI Official Synonym Symbols
PLP; PMD; HLD1; MMPL; SPG2; GPM6C; PLP/DM20
NCBI Protein Information
myelin proteolipid protein; lipophilin; major myelin proteolipid protein
UniProt Protein Name
Myelin proteolipid protein
UniProt Gene Name
PLP1
UniProt Synonym Gene Names
PLP; PLP
UniProt Entry Name
MYPR_HUMAN
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Product Notes
The PLP1 plp1 (Catalog #AAA254733) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PLP1 Antibody, Rabbit Polyclonal reacts with Human, Mouse, Rat Predicted to React with: Cynomolgus (Species predicted to react based on 100% sequence homology) and may cross-react with other species as described in the data sheet. AAA Biotech's PLP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PLP1 plp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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