Mouse PP2A alpha Monoclonal Antibody | anti-PP2A alpha antibody
Mouse Anti-PP2A alpha (methyl L309) [2A10]
Reactivity
Mouse, Human, Saccharomyces cerevisiae
Applications
Immunoprecipitation, Western Blot
Purity
Protein G
Synonyms
PP2A alpha, Antibody; Mouse Anti-PP2A alpha (methyl L309) [2A10]; PP2A alpha antibody; PP2A C antibody; PP2A-alpha antibody; PP2AA_HUMAN antibody; PP2Ac antibody; PP2CA antibody; PPP2CA antibody; Protein phosphatase 2, catalytic subunit, alpha isoform antibody; Replication protein C antibody; anti-PP2A alpha antibody
Host
Mouse
Reactivity
Mouse, Human, Saccharomyces cerevisiae
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2A10
Specificity
Alpha + beta isoforms of PP2A C
Purity/Purification
Protein G
Form/Format
Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PP2A alpha antibody
IP (Immunoprecipitation), WB (Western Blot)
Target Antigen
PP2A alpha (methyl L309)
Immunogen
C-terminal peptide (Methyl-Leu309) of human PP2A catalic subunit.
Myeloma/fusion Partners
X63-Ag8.653
Health & Safty
Products that contain sodium azide (a poisonous and hazardous substance) should be handled by trained staffs only.
Preparation and Storage
Store at 4 degree C for one month, or in small aliquots at -20 degree C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.
References
Benziane B et al. Activation of AMP-activated Protein Kinase Stimulates Na+,K+-ATPase Activity in Skeletal Muscle Cells. J Biol Chem 287:23451-63 (2012). WB PUBMED Li T et al. Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by a4 Protein in HEK293 Cells. Int J Biol Sci 7:740-52 (2011). WB ; Human PUBMED Finnegan S et al. A stress survival response in retinal cells mediated through inhibition of the serine / threonine phosphatase PP2A. Eur J Neurosci : (2010). WB ; Mouse PUBMED Hombauer H et al. Generation of active protein phosphatase 2A is coupled to holoenzyme assembly. PLoS Biol 5:e155 (2007) PUBMED Sontag E et al. Downregulation of protein phosphatase 2A carboxyl methylation and methyltransferase may contribute to Alzheimer disease pathogenesis. J Neuropathol Exp Neurol 63:1080-91 (2004) PUBMED Sontag E et al. Altered expression levels of the protein phosphatase 2A ABalphaC enzyme are associated with Alzheimer disease pathology. J Neuropathol Exp Neurol 63:287-301 (2004) PUBMED Fellner T et al. A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. Genes Dev 17:2138-50 (2003) PUBMED
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Product Notes
The PP2A alpha (Catalog #AAA59513) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-PP2A alpha (methyl L309) [2A10] reacts with Mouse, Human, Saccharomyces cerevisiae and may cross-react with other species as described in the data sheet. AAA Biotech's PP2A alpha can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the PP2A alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP2A alpha, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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