Rabbit Prostate Specific Antigen (PSA) Monoclonal Antibody | anti-PSA antibody

Prostate Specific Antigen (PSA)

Cat. Num. AAA214764

• Gene Names: KLK3; APS; PSA; hK3; KLK2A1
• Reactivity: Human. Others not known.
• Applications: Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Prostate Specific Antigen (PSA), Antibody; Prostate Specific Antigen (PSA); Antigen; prostate-specific (APS); Gamma-seminoprotein; hK3; Kallikrein related peptidase 3; Kallikrein-3 (KLK3); KLK2A1; P-30 antigen; Semenogelase; Seminin; anti-PSA antibody

• Host: Rabbit
• Reactivity: Human. Others not known.
• Clonality: Monoclonal
• Isotype: IgG
• Clone Number: KLK3/2871R
• Specificity: Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 238

• Applicable Applications for anti-PSA antibody: IHC (Immunohistochemistry)
• Immunogen: Recombinant full-length human KLK3 protein
• Positive Control: PC12 Cells or Normal Prostate or Prostate Carcinoma
• Cellular Localization: Cytoplasmic
• Chromosome Location: 19q13.33
• Preparation and Storage: Antibody with azide - store at 2 to 8 degree C.; Antibody without azide - store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified PSA Rabbit Recombinant Monoclonal Antibody (KLK3/2871R). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PSA Rabbit Recombinant Monoclonal Antibody (KLK3/2871R).)

Related Product Information for anti-PSA antibody

Recombinant Rabbit Monoclonal Antibody

References

Huang et al. 21/3; 483-490 (2005).

NCBI and Uniprot Product Information

• NCBI GI #: 71834853
• NCBI GeneID: 354
• NCBI Accession #: NP_001025218.1
• NCBI GenBank Nucleotide #: NM_001030047.1
• UniProt Accession #: P07288; Q15096; Q16272; Q86TG8; Q8IXI4; C9JXH3; G3V0H4; G3XAE3
• Molecular Weight: 33-34kDa
• NCBI Official Full Name: prostate-specific antigen isoform 3 preproprotein
• NCBI Official Synonym Full Names: kallikrein related peptidase 3
• NCBI Official Symbol: KLK3
• NCBI Official Synonym Symbols: APS; PSA; hK3; KLK2A1
• NCBI Protein Information: prostate-specific antigen
• UniProt Protein Name: Prostate-specific antigen
• UniProt Gene Name: KLK3
• UniProt Synonym Gene Names: APS; PSA; Seminin