WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPN11 protein (Right) or empty vector (Left) detected with PTPN11 antibody)
Mouse PTPN11 Monoclonal Antibody | anti-PTPN11 antibody
PTPN11 antibody
Gene Names
PTPN11; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
PTPN11 antibody was purified by affinity chromatography.
Synonyms
PTPN11, Antibody; PTPN11 antibody; Monoclonal PTPN11; Anti-PTPN11; Protein tyrosine phosphatase non-receptor type 11; PTP2C; SHP2; BPTP3; Protein-tyrosine phosphatase 1D; PTPN11; PTPN 11; PTPN-11; anti-PTPN11 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
3F2
Purity/Purification
PTPN11 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
0.99 mg/mL (varies by lot)
Sequence Length
593
Applicable Applications for anti-PTPN11 antibody
WB (Western Blot), FCM/FACS (Flow Cytometry)
Biological Significance
PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitoticcycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function asphospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for adiversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cellmigration.
Cross-Reactivity
Human, Mouse, Rat, Dog
Immunogen
Full length human recombinant protein of human PTPN11 produced in HEK293T cells.
Preparation and Storage
Store at 4 degree C for short term storage.
Store at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
Store at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPN11 protein (Right) or empty vector (Left) detected with PTPN11 antibody)
WB (Western Blot)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PTPN11 protein (Right) or empty vector (Left) detected with PTPN11 antibody)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of Hela cells using PTPN11 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
FCM/FACS (Flow Cytometry)
(Flow Cytometric analysis of Hela cells using PTPN11 antibody (Red), compared to a nonspecific negative control antibody (Blue).)
Related Product Information for anti-PTPN11 antibody
Mouse monoclonal PTPN11 antibody
Product Categories/Family for anti-PTPN11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 11 isoform 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 11
NCBI Official Symbol
PTPN11
NCBI Official Synonym Symbols
CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 11
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 11
UniProt Gene Name
PTPN11
UniProt Synonym Gene Names
PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2
UniProt Entry Name
PTN11_HUMAN
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Product Notes
The PTPN11 ptpn11 (Catalog #AAA107373) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PTPN11 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the PTPN11 ptpn11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPN11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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