Rabbit anti-Human Pulmonary Surfactant-Associated Protein D (SFTPD) Monoclonal Antibody | anti-SFTPD antibody

Pulmonary Surfactant-Associated Protein D (SFTPD) Recombinant Rabbit Monoclonal Antibody [Clone SFTPD/7085R]

Cat. Num. AAA215917

• Gene Names: SFTPD; SP-D; PSP-D; SFTP4; COLEC7
• Reactivity: Human
• Applications: Immunohistochemistry
• Synonyms: Pulmonary Surfactant-Associated Protein D (SFTPD), Antibody; Pulmonary Surfactant-Associated Protein D (SFTPD) Recombinant Rabbit Monoclonal Antibody [Clone SFTPD/7085R]; COLEC7; Collectin-7; Lung surfactant protein D; PSP-D Surfactant protein D; PSPD; Pulmonary surfactant associated protein PSP-D; SFTP 4; SFTP4; SFTPD; SP-D; Surfactant associated protein pulmonary 4; anti-SFTPD antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit/IgG
• Clone Number: SFTPD/7085R
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Concentration: Purified Ab with BSA and Azide at 200ug/ml; OR; Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)

• Applicable Applications for anti-SFTPD antibody: IHC (Immunohistochemistry)
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant fragment (around aa241-336) of human SFTPD protein (exact sequence is proprietary)
• Cellular Localization: Secreted
• Positive Control: Epithelial cells of the lung, skin, small intestine or bladder.
• Hu-chromosome Location: 10q22.3
• Unigene: 253495
• Preparation and Storage: Antibody with azide: store at 2 to 8 degree C; Antibody without azide: store at -20 to -80 degree C; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human lung stained with Surfactant Protein D Recombinant Rabbit Monoclonal (SFTPD/7085R).)

Related Product Information for anti-SFTPD antibody

Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

NCBI and Uniprot Product Information

• NCBI GI #: 61699226
• NCBI GeneID: 6441
• NCBI Accession #: NP_003010.4
• NCBI GenBank Nucleotide #: NM_003019.4
• UniProt Accession #: P35247; Q5T0M3; Q6FH08; Q86YK9; Q8TCD8; Q9UCJ2; Q9UCJ3
• Molecular Weight: 37,728 Da
• NCBI Official Full Name: pulmonary surfactant-associated protein D
• NCBI Official Synonym Full Names: surfactant protein D
• NCBI Official Symbol: SFTPD
• NCBI Official Synonym Symbols: SP-D; PSP-D; SFTP4; COLEC7
• NCBI Protein Information: pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4
• UniProt Protein Name: Pulmonary surfactant-associated protein D
• UniProt Gene Name: SFTPD
• UniProt Synonym Gene Names: COLEC7; PSPD; SFTP4; PSP-D; SP-D
• UniProt Entry Name: SFTPD_HUMAN