IHC (Immunohiostchemistry)
(IHC of S100A8/MRP8 on an FFPE Bone Marrow tissue)
Rabbit anti-Human S100A8/MRP8 Monoclonal Antibody | anti-S100A8/MRP8 antibody
S100A8/MRP8 (RBT-MRP8), RMab
Reactivity
Human
Synonyms
S100A8/MRP8, Antibody; S100A8/MRP8 (RBT-MRP8), RMab; S100A8/MRP8, (RBT-S100A8/MRP8); TFF3; trefoil factor 3 intestinal; ITF; P1B; TFI; anti-tff3; anti-itf; anti-S100A8/MRP8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-MRP8
Form/Format
This antibody is derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide.
Localization
Cytoplasmic
Intended Use
S100A8/MRP8 (RBT-MRP8), rabbit monoclonal antibody, is a primary antibody intended for laboratory use by trained laboratory personnel in an immunohistochemical (IHC) assay to qualitatively identify the S100A8/MRP8 protein by light microscopy in normal and/or pathological formalin-fixed, paraffin-embedded (FFPE) human tissue.
The clinical interpretation of any staining or its absence should be performed by a qualified pathologist and complemented by morphological studies using proper controls and evaluated within the context of the patient’s clinical history and other tests.
The clinical interpretation of any staining or its absence should be performed by a qualified pathologist and complemented by morphological studies using proper controls and evaluated within the context of the patient’s clinical history and other tests.
IHC (Immunohiostchemistry)
(IHC of S100A8/MRP8 on an FFPE Bone Marrow tissue)
IHC (Immunohiostchemistry)
(IHC of S100A8/MRP8 on an FFPE Bone Marrow tissue)
Dilution Info
Dilution Info
Related Product Information for anti-S100A8/MRP8 antibody
Myeloid Related Protein 8 (MRP8), also known as S100A8, is a calcium binding protein that belongs to the S100 family. By a Ca2+ dependent manner, S100A8/A9 forms Calprotectin, a heterodimeric inflammatory mediator of inflammation found in the cytoplasm of neutrophils and expressed on the membrane of monocytes. S100A8 is expressed during myeloid differentiation and chronic inflammations, and it is expressed constitutively or induced in epithelial cells during dermatose. S100A8 is expressed in cells with myeloid origin, including granulocytes, monocytes and macrophages, and it is observed in blood granulocytes and monocytes. It is also expressed in infiltrate macrophages during inflammatory reactions, but not in normal tissue macrophages. S100A8 also reacts with activated microglial cells in human cerebral malaria. In tumors, positive staining of S100A8 has been observed in various cancers including pancreatic cancer, and it has been linked to inflammation-associated cancers.
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Product Notes
The S100A8/MRP8 (Catalog #AAA59498) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The S100A8/MRP8 (RBT-MRP8), RMab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "S100A8/MRP8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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