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product-image-AAA46505_IHC11.jpg IHC (Immunohistochemisry) (Anti- S100A8 Picoband antibody, AAA46505, IHC(P)IHC(P): Rat Spleen Tissue)

anti-Mouse, Rat MRP8 Polyclonal Antibody | anti-MRP8 antibody

Anti-MRP8 Antibody

Gene Names
S100a8; p8; B8Ag; CFAg; Caga; MRP8; CP-10; 60B8Ag; AI323541
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
MRP8, Antibody; Anti-MRP8 Antibody; Protein S100-A8; 60B8Ag; AI323541; B8Ag; BEE11; CAGA; Calgranulin-A; Calprotectin L1L subunit; Calprotectin, included; CFAG; CGLA; Chemotactic cytokine CP-10; CP-10; Cystic fibrosis antigen; L1Ag; Leukocyte L1 complex light chain; MA387; MIF; Migration inhibitory factor-related protein 8; MRP-8; Myeloid-related protein 8; Neutrophil cytosolic 7 kDa protein; NIF; p8; Pro-inflammatory S100 cytokine; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A8; S100 calcium-binding protein A8; S100A8; S100A8/S100A9 complex, included; S10A8_HUMAN; Urinary stone protein band A; anti-MRP8 antibody
Ordering
Reactivity
Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
89
Applicable Applications for anti-MRP8 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived mouse MRP8 recombinant protein (Position: P2-E89). Mouse MRP8 shares 58.6% and 80.5% amino acid (aa) sequence identity with human and rat MRP8, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohistochemisry)

(Anti- S100A8 Picoband antibody, AAA46505, IHC(P)IHC(P): Rat Spleen Tissue)

product-image-AAA46505_IHC11.jpg IHC (Immunohistochemisry) (Anti- S100A8 Picoband antibody, AAA46505, IHC(P)IHC(P): Rat Spleen Tissue)

IHC (Immunohiostchemistry)

(Anti- S100A8 Picoband antibody, AAA46505, IHC(P)IHC(P): Mouse Spleen Tissue)

product-image-AAA46505_IHC13.jpg IHC (Immunohiostchemistry) (Anti- S100A8 Picoband antibody, AAA46505, IHC(P)IHC(P): Mouse Spleen Tissue)

WB (Western Blot)

(Anti- S100A8 Picoband antibody, AAA46505, Western blottingAll lanes: Anti S100A8 (AAA46505) at 0.5ug/mlWB: Mouse Spleen Tissue Lysate at 50ugPredicted bind size: 11KDObserved bind size: 19KD)

product-image-AAA46505_WB15.jpg WB (Western Blot) (Anti- S100A8 Picoband antibody, AAA46505, Western blottingAll lanes: Anti S100A8 (AAA46505) at 0.5ug/mlWB: Mouse Spleen Tissue Lysate at 50ugPredicted bind size: 11KDObserved bind size: 19KD)
Related Product Information for anti-MRP8 antibody
Description: Rabbit IgG polyclonal antibody for Protein S100-A8(S100A8) detection. Tested with WB, IHC-P in Mouse;Rat.

Background: S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene. It is also known as calgranulin A. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
References
1. "Entrez Gene: S100A8 S100 calcium binding protein A8". 2. Kerkhoff C, Klempt M, Sorg C (1999). "Novel insights into structure and function of MRP8 (S100A8) and MRP14 (S100A9).". Biochim. Biophys. Acta 1448 (2): 200-11. 3. Schäfer T, Sachse GE, Gassen HG (1991). "The calcium-binding protein MRP-8 is produced by human pulmonary tumor cells.". Biol. Chem. Hoppe-Seyler 372 (1): 1-4.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,295 Da
NCBI Official Full Name
protein S100-A8
NCBI Official Synonym Full Names
S100 calcium binding protein A8 (calgranulin A)
NCBI Official Symbol
S100a8
NCBI Official Synonym Symbols
p8; B8Ag; CFAg; Caga; MRP8; CP-10; 60B8Ag; AI323541
NCBI Protein Information
protein S100-A8
UniProt Protein Name
Protein S100-A8
UniProt Gene Name
S100a8
UniProt Synonym Gene Names
Caga; Mrp8; MRP-8; p8
UniProt Entry Name
S10A8_MOUSE

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Product Notes

The MRP8 s100a8 (Catalog #AAA46505) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-MRP8 Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRP8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MRP8 s100a8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRP8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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