IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon carcinoma stained with SATB2 Rabbit Recombinant Monoclonal Antibody (SATB2/4374R).)
Rabbit anti-Human SATB2 Monoclonal Antibody | anti-SATB2 antibody
SATB2 (Colorectal Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone SATB2/4374R]
Gene Names
SATB2; GLSS
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
SATB2, Antibody; SATB2 (Colorectal Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone SATB2/4374R]; SATB2 (Colorectal Carcinoma Marker); DNA-binding protein SATB2; GLSS; SATB homeobox 2; Special AT-rich sequence-binding protein 2; anti-SATB2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
SATB2/4374R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-SATB2 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Synthetic peptide corresponding to residues within aa200-300 corresponding to human SATB2
Cellular Localization
Nuclear
Positive Control
Human colon or cerebral cortex tissue.
Hu-chromosome Location
2q33.1
Unigene
516617
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon carcinoma stained with SATB2 Rabbit Recombinant Monoclonal Antibody (SATB2/4374R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human colon carcinoma stained with SATB2 Rabbit Recombinant Monoclonal Antibody (SATB2/4374R).)
Related Product Information for anti-SATB2 antibody
SATB2 is a DNA binding protein that specifically binds nuclear matrix attachment regions. It is involved in transcription regulation and chromatin remodeling. SATB2 expression in colorectal carcinomas (CRC) is correlated with good prognosis and in laryngeal squamous cell carcinoma it functions as a tumor suppressor wherein loss of expression is positively correlated with high tumor grade and recurrence. Moreover, SATB2, in combination with CK20, could identify almost all CRC s. Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2, and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2. Additionally, SATB2 antibody can identify neuroendocrine neoplasms of colon and rectum because SATB2 is usually negative in neuroendocrine neoplasms of the GI tract, pancreas, and lung. More recently, it has been reported that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
69,137 Da
NCBI Official Full Name
DNA-binding protein SATB2
NCBI Official Synonym Full Names
SATB homeobox 2
NCBI Official Symbol
SATB2
NCBI Official Synonym Symbols
GLSS
NCBI Protein Information
DNA-binding protein SATB2; SATB family member 2; special AT-rich sequence-binding protein 2
UniProt Protein Name
DNA-binding protein SATB2
UniProt Gene Name
SATB2
UniProt Synonym Gene Names
KIAA1034
UniProt Entry Name
SATB2_HUMAN
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Product Notes
The SATB2 satb2 (Catalog #AAA215659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SATB2 (Colorectal Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone SATB2/4374R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SATB2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SATB2 satb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SATB2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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