Rabbit SATB2 Polyclonal Antibody | anti-SATB2 antibody

SATB2 Antibody

Cat. Num. AAA39642

• Gene Names: SATB2; GLSS
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: SATB2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: SATB2, Antibody; SATB2 Antibody; SATB2; KIAA1034; DNA-binding protein SATB2; Special AT-rich sequence-binding protein 2; SATB homeobox 2; anti-SATB2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms of SATB2 are known to exist. This SATB2 antibody will not cross-react with SATB1.
• Purity/Purification: SATB2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 733

• Applicable Applications for anti-SATB2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: SATB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human SATB2.
• Buffer: SATB2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: SATB2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of SATB2 in Human Brain cells with SATB2 antibody at 50 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of SATB2 in human brain with SATB2 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of SATB2 in A20 cell lysate with SATB2 antibody at (A) 2 and (B) 4 μg/mL.)

Related Product Information for anti-SATB2 antibody

SATB2 Antibody: Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development.

NCBI and Uniprot Product Information

• NCBI GI #: 13634020
• NCBI GeneID: 23314
• UniProt Accession #: Q9UPW6; Q3ZB87; Q4V763; A8K5Z8
• Molecular Weight: 69,137 Da
• NCBI Official Full Name: DNA-binding protein SATB2
• NCBI Official Synonym Full Names: SATB homeobox 2
• NCBI Official Symbol: SATB2
• NCBI Official Synonym Symbols: GLSS
• NCBI Protein Information: DNA-binding protein SATB2; SATB family member 2; special AT-rich sequence-binding protein 2
• UniProt Protein Name: DNA-binding protein SATB2
• UniProt Gene Name: SATB2
• UniProt Synonym Gene Names: KIAA1034
• UniProt Entry Name: SATB2_HUMAN