Application Data
Mouse Shank3 Monoclonal Antibody | anti-SHANK3 antibody
Anti-Shank3 Monoclonal Antibody
Gene Names
SHANK3; PSAP2; SCZD15; PROSAP2; SPANK-2; KIAA1650; DEL22q13.3
Reactivity
Human, mouse, rat
Applications
Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Immunoblot, Western Blot
Synonyms
Shank3, Antibody; Anti-Shank3 Monoclonal Antibody; anti-SHANK3 antibody
Host
Mouse
Reactivity
Human, mouse, rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
S69-46
Specificity
Shank3
This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2.
This antibody recognizes human, mouse, and rat Shank3. It does not cross-react with Shank1 or Shank2.
Form/Format
100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
Sequence Positions
840-857
Applicable Applications for anti-SHANK3 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), IB (Immunoblot)
Antigen
Synthetic peptide corresponding to aa 840-857 (PEKLPGSLRKGIPRTKSV) of rat Shank3 (accession no. Q9JLU4).
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Application Data
Application Data
Related Product Information for anti-SHANK3 antibody
Shank proteins are a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Shank proteins are crucial in receptor tyrosine kinase signaling; specifically, Shank3 can mediate Erk-MAPK and P13K signaling which is crucial for tubule formation. Shank 3 is also one of the latest genes to be associated with autism. A mutation in a single copy of Shank3 on chromosome 22q13 can result in communication disorders.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
SH3 and multiple ankyrin repeat domains protein 3
NCBI Official Synonym Full Names
SH3 and multiple ankyrin repeat domains 3
NCBI Official Symbol
SHANK3
NCBI Official Synonym Symbols
PSAP2; SCZD15; PROSAP2; SPANK-2; KIAA1650; DEL22q13.3
NCBI Protein Information
SH3 and multiple ankyrin repeat domains protein 3; shank postsynaptic density protein; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2
UniProt Protein Name
SHANK3
UniProt Gene Name
SHANK3
UniProt Entry Name
Q3S3B4_HUMAN
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Product Notes
The SHANK3 shank3 (Catalog #AAA47744) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 840-857. The Anti-Shank3 Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Shank3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), IHC (Immunohistochemistry), IB (Immunoblot). Researchers should empirically determine the suitability of the SHANK3 shank3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Shank3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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