FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
Mouse anti-Human SMNDC1 Monoclonal Antibody | anti-SMNDC1 antibody
SMNDC1 Mouse Monoclonal Antibody [Clone PCRP-SMNDC1-1A9]
Gene Names
SMNDC1; SMNR; SPF30; TDRD16C
Reactivity
Human
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
SMNDC1, Antibody; SMNDC1 Mouse Monoclonal Antibody [Clone PCRP-SMNDC1-1A9]; 30kDa splicing factor SMNrp; MGC106917; MGC112663; SMN related protein; SMNR; SPF30; Splicing factor 30, survival of motor neuron-related; Survival motor neuron domain containing protein 1; Survival of motor neuron related splicing factor 30; anti-SMNDC1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2b
Clone Number
PCRP-SMNDC1-1A9
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-SMNDC1 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant full-length human SMNDC1 protein
Cellular Localization
Nucleus, Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies
Positive Control
HeLa or HepG2 cells.
Hu-chromosome Location
10q25.2
Unigene
632093
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of PFA-fixed HeLa cells. SMNDC1 Mouse Monoclonal Antibody (PCRP-SMNDC1-1A9) followed by goat anti-mouse IgG-CF488 (blue); unstained cells (red).)
Related Product Information for anti-SMNDC1 antibody
SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (survival motor neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest at prespliceosomes (A complex). This supports a function for SPF30 in mediating the incorporation/recruitment of U4/U5/U6 tri-snRNP to the prespliceosome. In addition, the overexpression of SPF30 can lead to apoptosis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
238
NCBI Official Full Name
Survival of motor neuron-related-splicing factor 30
NCBI Official Synonym Full Names
survival motor neuron domain containing 1
NCBI Official Symbol
SMNDC1
NCBI Official Synonym Symbols
SMNR; SPF30; TDRD16C
NCBI Protein Information
survival of motor neuron-related-splicing factor 30; SMN-related protein; tudor domain containing 16C; 30 kDa splicing factor SMNrp; survival motor neuron domain-containing protein 1; splicing factor 30, survival of motor neuron-related
UniProt Protein Name
Survival of motor neuron-related-splicing factor 30
UniProt Gene Name
SMNDC1
UniProt Synonym Gene Names
SMNR; SPF30
UniProt Entry Name
SPF30_HUMAN
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Product Notes
The SMNDC1 smndc1 (Catalog #AAA215518) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SMNDC1 Mouse Monoclonal Antibody [Clone PCRP-SMNDC1-1A9] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SMNDC1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the SMNDC1 smndc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMNDC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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