Application Data
(The purity of Anti-SOST / Sclerostin Reference Antibody (setrusumab)is more than 91.76% ,determined by SEC-HPLC.)
SOST/Sclerostin Recombinant Antibody | SOST recombinant antibody
Anti-SOST/Sclerostin Reference Antibody (setrusumab)
Gene Names
SOST; CDD; VBCH
Reactivity
Human, Mouse
Applications
Functional Assay, Flow Cytometry, Functional Assay
Purity
This antibody is purified through a protein A column.
Synonyms
SOST/Sclerostin, Recombinant Antibody; Anti-SOST/Sclerostin Reference Antibody (setrusumab); SOST recombinant antibody
Host
CHO Cell
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2SA
Specificity
SOST/Sclerostin
Purity/Purification
This antibody is purified through a protein A column.
Form/Format
Purified monoclonal antibody supplied in PBS, pH6.0, without preservative.
Concentration
2.96 mg/ml (varies by lot)
Applicable Applications for SOST recombinant antibody
FA (Functional Assay), FCM/FACS (Flow Cytometry)
Endotoxin
< 0.001EU/ ug,determined by LAL method.
Conjugation
Unconjugated
Expression system
CHO Cell
Function
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Cellular Location
Secreted, extracellular space, extracellular matrix
Tissue Location
Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level).
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -20°C in small aliquots to prevent freeze/thaw cycles
Application Data
(The purity of Anti-SOST / Sclerostin Reference Antibody (setrusumab)is more than 91.76% ,determined by SEC-HPLC.)
Application Data
(The purity of Anti-SOST / Sclerostin Reference Antibody (setrusumab)is more than 91.76% ,determined by SEC-HPLC.)
SDS-PAGE
(Anti-SOST / Sclerostin Reference Antibody (setrusumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
SDS-PAGE
(Anti-SOST / Sclerostin Reference Antibody (setrusumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%)
Product Categories/Family for SOST recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
143.44 KDa
NCBI Official Full Name
sclerostin
NCBI Official Synonym Full Names
sclerostin
NCBI Official Symbol
SOST
NCBI Official Synonym Symbols
CDD; VBCH
NCBI Protein Information
sclerostin
UniProt Protein Name
Sclerostin
UniProt Gene Name
SOST
UniProt Entry Name
SOST_HUMAN
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Product Notes
The SOST sost (Catalog #AAA297111) is a Recombinant Antibody produced from CHO Cell and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOST/Sclerostin Reference Antibody (setrusumab) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SOST/Sclerostin can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the SOST sost for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOST/Sclerostin, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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