Mouse SUMO-1 Monoclonal Antibody | anti-SUMO1 antibody

SUMO-1 Mouse Monoclonal Antibody

Cat. Num. AAA62742

• Gene Names: SUMO1; DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
• Reactivity: Human, Rat.; Predicted to show a broad species reactivity
• Applications: Immunohistochemistry, Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
• Synonyms: SUMO-1, Antibody; SUMO-1 Mouse Monoclonal Antibody; GAP-modifying protein 1; GMP1; OFC10; PIC1; SENP2; Sentrin 1; Small ubiquitin-related modifier 1; SMT3; SMT3 suppressor of mif two 3 homolog 1; SMT3C; SMT3H3; Ubiquitin homology domain protein PIC1; Ubiquitin Like 1; Ubiquitin like protein UBL1; anti-SUMO1 antibody

• Host: Mouse
• Reactivity: Human, Rat.; Predicted to show a broad species reactivity
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: SUMO1/1188
• Specificity: This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 101

• Applicable Applications for anti-SUMO1 antibody: IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
• Cellular Localization: Predominantly nuclear with some cytoplasmic
• Immunogen: Recombinant human SUMO1 protein
• Hu-Chromosome Location: 2q33.1
• Positive Control: Breast carcinoma
• Preparation and Storage: Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded Rat Pancreas stained with SUMO-1 Monoclonal Antibody (SUMO1/1188))

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Tonsil stained with SUMO-1 Monoclonal Antibody (SUMO1/1188))

IHC (Immunohistochemisry)

(Formalin-fixed, paraffin-embedded human Tonsil stained with SUMO-1 Monoclonal Antibody (SUMO1/1188))

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with SUMO-1 Monoclonal Antibody (SUMO1/1188))

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with SUMO-1 Monoclonal Antibody (SUMO1/1188))

NCBI and Uniprot Product Information

• NCBI GI #: 54792065
• NCBI GeneID: 7341
• NCBI Accession #: NP_001005781.1
• NCBI GenBank Nucleotide #: NM_001005781.1
• UniProt Accession #: P63165; P55856; Q6FGG0; Q6NZ62; Q93068; A8MUS8; B2R4I5
• Molecular Weight: 11.5kDa (Monomer); 90kDa (Heteromer)
• NCBI Official Full Name: small ubiquitin-related modifier 1 isoform a
• NCBI Official Synonym Full Names: small ubiquitin-like modifier 1
• NCBI Official Symbol: SUMO1
• NCBI Official Synonym Symbols: DAP1; GMP1; PIC1; SMT3; UBL1; OFC10; SENP2; SMT3C; SMT3H3
• NCBI Protein Information: small ubiquitin-related modifier 1
• UniProt Protein Name: Small ubiquitin-related modifier 1
• UniProt Gene Name: SUMO1
• UniProt Synonym Gene Names: SMT3C; SMT3H3; UBL1; SUMO-1; GMP1; Smt3C
• UniProt Entry Name: SUMO1_HUMAN