Tau Recombinant Antibody | MAPT recombinant antibody

Phospho-Tau (Ser202, Thr205) Antibody, Rabbit MAb

Cat. Num. AAA259422

• Reactivity: Human
• Applications: Western Blot
• Purity: Protein A
• Synonyms: Tau, Recombinant Antibody; Phospho-Tau (Ser202, Thr205) Antibody, Rabbit MAb; microtubule-associated protein tau; Anti-DDPAC Antibody; Anti-FLJ31424 Antibody; Anti-FTDP-17 Antibody; Anti-MAPTL Antibody; Anti-MGC138549 Antibody; Anti-MSTD Antibody; Anti-MTBT1 Antibody; Anti-MTBT2 Antibody; Anti-PPND Antibody; Anti-PPP1R103 Antibody; Anti-TAU Antibody; Anti-tau-40 Antibody; Anti-Tau-PHF6 Antibody; MAPT recombinant antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: 0016
• Specificity: Human, Mouse, Rat; Species predicted to react based on 100% sequence homology: Cynomolgus; Phospho-Tau (Ser202, Thr205) of P10636-8 in UniProt, which corresponds to Phospho-Tau (Ser519, Thr522) of P10636-1 in UniProt.
• Purity/Purification: Protein A
• Form/Format: Liquid; 10 mM sodium HEPES, 150 mM NaCl, 100ug/mL BSA, 50% glycerol, pH 7.5

• Applicable Applications for MAPT recombinant antibody: WB (Western Blot)
• Immunogen: A synthetic phosphopeptide corresponding to residues around (Ser202, Thr205) of the Human Phospho-Tau
• Preparation: This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around (Ser202, Thr205) of the Human Phospho-Tau.
• Preparation and Storage: This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.; This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

WB (Western Blot)

(Western blot analysis of extracts from rat brain using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody (#AAA259422) at 1:5000 dilution.)

WB (Western Blot)

(Western blot analysis of extracts from mouse brain (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-Tau (Ser202, Thr205) rabbit monoclonal Antibody (#AAA259422) at 1:2000 dilution.(Validation Experiment))

Related Product Information for MAPT recombinant antibody

MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development-possibly because of compensation in tau deficiency by other MAPs.

Product Categories/Family for MAPT recombinant antibody

AMPK Signaling Pathway

References

Harad. A. e. al. (1994. Altere. microtubul. organizatio. i. small-calibr. axon. o. mic. lackin. ta. protein. Nature. 369(6480):488-91. Weingarte. MD. e. al. (1975. . protei. facto. essentia. fo. microtubul. assembly. Pro. Nat. Aca. Sci. 72(5):1858-62. Goeder. M. e. al. (1989. Multipl. isoform. o. huma. microtubule-associate. protei. tau. sequence. an. localizatio. i. neurofibrillar. tangle. o. Alzheimer'. disease. Neuron. 3(4). 519-26.