Application Data
(Surface Staining of human peripheral blood lymphocytes with Mouse anti Human TCR gamma/delta:RPE)
Mouse anti-Human TCR Gamma/Delta Monoclonal Antibody | anti-CD3E antibody
Mouse Anti Human TCR Gamma/Delta
Gene Names
CD3E; T3E; TCRE; IMD18
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
>95% by SDS PAGEPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Synonyms
TCR Gamma/Delta, Antibody; Mouse Anti Human TCR Gamma/Delta; TCR Gamma/Delta antibody, B1; anti-CD3E antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
B1
Purity/Purification
>95% by SDS PAGE
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Form/Format
Purified IgG - Liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
207
Applicable Applications for anti-CD3E antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
Preservative Stabilizers
<0.1% Sodium Azide (NaN3)
Buffer Solution
Phosphate Buffered Saline
Preparation and Storage
Store at 4 degree C. DO NOT FREEZE.
This product should be stored undiluted.
This product should be stored undiluted.
Application Data
(Surface Staining of human peripheral blood lymphocytes with Mouse anti Human TCR gamma/delta:RPE)
Application Data
(Surface Staining of human peripheral blood lymphocytes with Mouse anti Human TCR gamma/delta:RPE)
Application Data
(Surface Staining of human peripheral blood lymphocytes with Mouse anti Human TCR gamma/delta:FITC)
Application Data
(Surface Staining of human peripheral blood lymphocytes with Mouse anti Human TCR gamma/delta:FITC)
Related Product Information for anti-CD3E antibody
Mouse anti Human TCR gamma/delta, clone B1 recognizes TCR gamma/delta, a T cell receptor expressed by a small subset of T cells. In healthy individuals these TCR gamma/delta cells account for 1-10% of peripheral blood lymphocytes (Gomes et al. 2010).
TCR gamma/delta is composed of disulfide bonded gamma and delta chains that can bind directly to pathogen derived glycoprotein's or non-classical MHC molecules on tumor cells (Kuhns et al. 2006).
This clone B1 has been used as a blocking antibody in experiments to examine the recognition of tumor cells by TCR gamma/delta cells. These experiments supported the hypothesis that innate NK receptors on gamma/delta cells can also bind and recognize tumor cells (Correia et al. 2011).
TCR gamma/delta is composed of disulfide bonded gamma and delta chains that can bind directly to pathogen derived glycoprotein's or non-classical MHC molecules on tumor cells (Kuhns et al. 2006).
This clone B1 has been used as a blocking antibody in experiments to examine the recognition of tumor cells by TCR gamma/delta cells. These experiments supported the hypothesis that innate NK receptors on gamma/delta cells can also bind and recognize tumor cells (Correia et al. 2011).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
T-cell surface glycoprotein CD3 epsilon chain
NCBI Official Synonym Full Names
CD3e molecule
NCBI Official Symbol
CD3E
NCBI Official Synonym Symbols
T3E; TCRE; IMD18
NCBI Protein Information
T-cell surface glycoprotein CD3 epsilon chain
UniProt Protein Name
T-cell surface glycoprotein CD3 epsilon chain
UniProt Gene Name
CD3E
UniProt Synonym Gene Names
T3E
UniProt Entry Name
CD3E_HUMAN
Similar Products
Product Notes
The CD3E cd3e (Catalog #AAA50392) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human TCR Gamma/Delta reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TCR Gamma/Delta can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD3E cd3e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCR Gamma/Delta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.