WB (Western Blot)
(Western blot of TLR8 in cell lysates from 293 transfected with human TLR8 using antibody at a concentration of 2 ug/ml.)
Mouse anti-Human, Mouse TLR8 Monoclonal Antibody | anti-TLR8 antibody
Mouse Monoclonal [clone 44C143] (IgG,k) to Human TLR8
Gene Names
TLR8; CD288
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot, Immunohistochemistry
Purity
Protein G Purified
Synonyms
TLR8, Antibody; Mouse Monoclonal [clone 44C143] (IgG,k) to Human TLR8; Anti-TLR8 Antibody (aa750-850, clone 44C143) IHC-plus; TLR8; CD288; Toll-like receptor 8; CD288 antigen; Human TLR8; anti-TLR8 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG,k
Clone Number
44C143
Specificity
A KLH-conjugated synthetic peptide of human TLR8, within amino acids 750-850. It will cross-react with mouse TLR8.
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.05% BSA, 0.05% sodium azide. Sourced in TCS.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1041
Applicable Applications for anti-TLR8 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide from human TLR8.
Immunogen Type
Synthetic peptide
Immunogen
TLR8 antibody was raised against synthetic peptide from human TLR8.
Antigen Modification
aa750-850
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
WB (Western Blot)
(Western blot of TLR8 in cell lysates from 293 transfected with human TLR8 using antibody at a concentration of 2 ug/ml.)
WB (Western Blot)
(Western blot of TLR8 in cell lysates from 293 transfected with human TLR8 using antibody at a concentration of 2 ug/ml.)
FCM/FACS (Flow Cytometry)
(Intracellular flow analysis of TLR8 in1x10^6 Ramos cells using 0.5 ug of antibody. Shaded histogram represents Ramos cells without antibody; green represents isotype control; purple represents anti-TLR8 antibody.)
FCM/FACS (Flow Cytometry)
(Intracellular flow analysis of TLR8 in1x10^6 Ramos cells using 0.5 ug of antibody. Shaded histogram represents Ramos cells without antibody; green represents isotype control; purple represents anti-TLR8 antibody.)
IHC (Immunohistochemistry)
(Anti-TLR8 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-TLR8 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Related Product Information for anti-TLR8 antibody
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA.
Product Categories/Family for anti-TLR8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
121,764 Da
NCBI Official Full Name
toll-like receptor 8 isoform 2
NCBI Official Synonym Full Names
toll-like receptor 8
NCBI Official Symbol
TLR8
NCBI Official Synonym Symbols
CD288
NCBI Protein Information
toll-like receptor 8
UniProt Protein Name
Toll-like receptor 8
UniProt Gene Name
TLR8
UniProt Entry Name
TLR8_HUMAN
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Product Notes
The TLR8 tlr8 (Catalog #AAA51803) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 44C143] (IgG,k) to Human TLR8 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TLR8 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TLR8 tlr8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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