ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using TORC1 mouse mAb (dilution 1:200).)
Mouse anti-Human, Mouse TORC1 Monoclonal Antibody | anti-CRTC1 antibody
TORC1 Antibody
Gene Names
CRTC1; MECT1; TORC1; TORC-1; WAMTP1
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot
Synonyms
TORC1, Antibody; TORC1 Antibody; Purified Mouse Monoclonal Antibody (Mab); KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1_HUMAN; FLJ14027; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1.; anti-CRTC1 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Form/Format
ascites
Sequence Length
650
Applicable Applications for anti-CRTC1 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Antigen Source
Human
Antigen Type
Recombinant Protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using TORC1 mouse mAb (dilution 1:200).)
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using TORC1 mouse mAb (dilution 1:200).)
WB (Western Blot)
(Western blot detection of TORC1 in Hela,mouse brain,SW480,COS7,C6 and 3T3 cell lysates using TORC1 mouse mAb (1:2000 diluted).Predicted band size:78KDa.Observed band size:78KDa.)
WB (Western Blot)
(Western blot detection of TORC1 in Hela,mouse brain,SW480,COS7,C6 and 3T3 cell lysates using TORC1 mouse mAb (1:2000 diluted).Predicted band size:78KDa.Observed band size:78KDa.)
Related Product Information for anti-CRTC1 antibody
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long- term potentiation (L-LTP) maintenance at the Schaffer collateral- CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
Product Categories/Family for anti-CRTC1 antibody
References
Iourgenko V.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:12147-12152(2003). Tonon G.,et al.Nat. Genet. 33:208-213(2003). Tonon G.,et al.Nat. Genet. 33:408-408(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Grimwood J.,et al.Nature 428:529-535(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67300
NCBI Official Full Name
CREB-regulated transcription coactivator 1 isoform 3
NCBI Official Synonym Full Names
CREB regulated transcription coactivator 1
NCBI Official Symbol
CRTC1
NCBI Official Synonym Symbols
MECT1; TORC1; TORC-1; WAMTP1
NCBI Protein Information
CREB-regulated transcription coactivator 1
UniProt Protein Name
CREB-regulated transcription coactivator 1
UniProt Gene Name
CRTC1
UniProt Synonym Gene Names
TORC-1; Transducer of CREB protein 1
UniProt Entry Name
CRTC1_HUMAN
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Product Notes
The CRTC1 crtc1 (Catalog #AAA290433) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TORC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TORC1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CRTC1 crtc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TORC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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